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News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… into four distinct molecular subtypes researchers with The Cancer Genome Atlas (TCGA) Network have found. In the study, published online July 23, 2014, in Nature , the scientists report that this discovery could … cells can look under a microscope, even when from the same tumor. The researchers hope that the new classification …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … and their collaborators have identified mutations in the TAF1 gene. They've also demonstrated that the mutation … Leja, NHGRI.  Dr. Bell and her team isolated DNA from tumor cells and from normal cells from patients with CCEC. …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … types, particularly in signaling pathways that promote tumor development and growth. The researchers developed a …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number of new … about the biology and development of a rare form of kidney cancer. … the cell's energy supplier. They also discovered that the tumor is characterized by genetic rearrangements near a gene …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… Breast cancer is the second most common cancer in women after skin cancer. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and … a common disease. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… A key challenge health care providers face in treating prostate cancer is distinguishing the aggressive, potentially … cancerous by producing proteins that fix damage to DNA. The research team used whole genome sequencing, a … DNA make-up of an organism at a single time, to look at tumor-specific mutations in aggressive prostate cancer. The …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United States. An estimated 40 to 50 percent of … Skin cancer is the most common type of cancer in the United … skin cancer. It occurs when melanocytes, the pigment cells in the lower part of the epidermis, become malignant, meaning …
News Release
The TCGA network describes uterine and bile duct cancer.
… The Cancer Genome Atlas (TCGA), a program co-funded by the National Cancer Institute and NHGRI, has greatly improved our … - outlining the molecular similarities between different cancer patients and cancer types, as well as documenting what … by healthy cells (in pink), illustrating a primary tumor spreading to other parts of the body through the …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified … potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease. They also discovered that, at the molecular …
Talking Glossary
El cáncer es una enfermedad en la que algunas células del cuerpo crecen fuera de control. Hay muchos tipos diferentes de cáncer, y cada uno comienza cuando una única célula adquiere un cambio genómico (o mutación) que le permite dividirse y multiplicarse sin control.