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News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… declare that their findings "may help shed light on pathways important for the development of vaccines and immune …
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… responses will improve scientists' understanding of cell pathways and aid in the development of new therapies for many … of cellular responses to address a wider range of basic biological and disease-related problems than was possible in … NIH awards aim to improve understanding of cell pathways, development of new therapies …
News Release
The Genetics and Public Policy and Genetics and Education Fellowships provide a pathway for scientists to pursue careers in science policy or education.
Profile
Dr. Pavan looks back on his career at NHGRI, highlights pivotal moments and shares his future plans in artistic woodworking and community mediation.
… doing genetics research, but also become experts the other biological field, which allowed us to make key discoveries. A … that focused on understanding genome function and gene pathways in development and disease. As head of the Genomics, … after nearly 30 years of discovering gene functions and pathways …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… have a comprehensive understanding of many of the genetic pathways that lead to cancers of the lung," said NCI Director …
Event
On January 11, 2021, NHGRI and The George Washington University organized an interactive webinar.
… we see population differences in illness? What social and biological factors are important? What is it like …
Event
Lectures series that increases understanding of genomics in the scholarly community and presents contemporary research of immediate interest to NHGRI staff.
Media Availability
New research provides a better understanding of some of the genetic and cellular changes in pathways and processes involved in Autism Spectrum Disorder.
… of some of the genetic and cellular changes in pathways and processes thought to be involved in ASD, and … identified variations and mutations in genes in three pathways that are important to normal development. In each case, the changes in these pathways were linked to autism risk. They include: Synaptic …
Educational Resources
An enzyme is a biological catalyst and is almost always a protein.
… An enzyme is a biological catalyst and is almost always a protein. … An enzyme is a biological catalyst and is almost always a protein. It speeds … An enzyme is a biological catalyst and is almost always a protein. …
Staff
Dr. Lawrence Brody is a senior investigator in NHGRI's Social and Behavioral Research Branch and director of NHGRI's Division of Genomics and Society.
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… mutations that lead to perturbations in normal metabolic pathways and cause disorders such as cancer and birth … of folate, vitamin B12, and homocysteine metabolic pathways. The team also established that genetic variants in … Lawrence Brody, genetic mutations, metabolic pathways, birth defects, ethical legal and social issues, …