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Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… genomic research for NHGRI investigators. As head of the Cancer Genomics Unit, his research efforts led to the … The Cancer Genomics Unit (CGU) focuses on adopting genomic … group in search of the gene responsible for early onset breast cancer ( BRCA1 ), CGU developed resources and aided in …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in 6 American men will develop prostate cancer … Age: A man's age is the strongest risk factor for prostate cancer. It is rare for a man to develop prostate cancer before the age of 40. After age 50 the chance of …
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… Investigators with The Cancer Genome Atlas (TCGA) Research Network have discovered … The researchers also uncovered new smoking-related cancer subtypes and potential new drug targets, and found numerous genomic similarities with other cancer types. Taken together, this study's findings may …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Receiving a cancer diagnosis can feel like losing control of everything. … its natural defenses, which can then lead to diseases like cancer," said Laura Elnitski, Ph.D., a senior investigator in … outcomes for different tumor types. For example, in breast cancers, CIMP is associated with a lower risk of …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… For many cancer patients and their doctors, the deadliest enemy is metastasis - the migration of cancer cells from the original tumor to other places in the body. In at least 90 percent of hard-tumor cancer deaths, the killer isn't the original cancer but …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… is a leader in the application of genome science to cancer research. His recent studies investigate the genetic … Asian Hepatocellular Carcinoma and Cholangiocarcinoma . Cancer Cell , 32(1):57-70.e3. 2017. Killian JK, Dorssers LC, … technologies, osteosarcoma profiling, melanoma profiling, breast cancer profiling, technology development …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated … for many human cancers, including aggressive skin cancer and cancer of the colon, rectum, ovary and thyroid. …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no detectable cancer. But, unfortunately, some patients will hear the word …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because … Canine transmissible venereal tumor, or CTVT, spreads when cancer cells move from one dog to the other during sexual … immune systems from detecting and fending off invading cancer cells. They reported their results online July 31, …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer. Individuals who have inherited mutations in certain …