Search Results
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Genome editing is a method that lets scientists change the DNA of … many organisms, including plants, bacteria, and animals. Editing DNA can lead to changes in physical traits, like eye … Genome editing technologies enable scientists to make changes to … add, or replace the DNA where it was cut. The first genome editing technologies were developed in the late 1900s. More …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
… the conversation about the science and ethics of genome editing has grown louder due to faster, cheaper, and more … media tends to focus on the potential use of genome editing in humans, the main application of this technology … will aid the development of new treatments, including gene therapy . …
Genomics and Medicine
Starting in 2019, the American Journal of Human Genetics has published an annual feature identifying ten key advances in applying genomic information to clinical care that were reported in the previous 12 months of published literature. The Genomic Medicine Working Group has authored these reviews, based on its broader effort to identify notable accomplishments in genomic medicine on a monthly basis. From this larger set of published accomplishments, the working group has continued to select ten papers annually to be highlighted as the most significant.
… hyperthermia 6. Treating inherited retinal disease with gene editing 7. Validation of a clinical breast cancer risk … may have greater diagnostic utility than a targeted gene panel in sick infants New, specific gene editing may treat sickle cell disease Read the full review: …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… runners-up include three relevant to genomics: " pinpoint gene editing ," " a cancer drug's broad swipe ," and " gene therapy triumph ." Nature's list of Science Events … In addition, the Senate held a hearing entitled "Gene Editing Technology: Innovation and Impact," which …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… It is important to understand the components of gene therapy, how these components differ and other treatment … cells to reduce your symptoms of sickle cell disease. Gene therapies use your own stem cells, while bone marrow … Types of gene therapy include gene addition and gene editing . There are two types of gene editing: gene silencing …
News Release
NHGRI hosted a CRISPR "Ask Me Anything" with Jennifer Doudna, Ph.D., reaching 10.5 million people worldwide.
… there to tackle some of the ethics questions related to gene editing. Here, we recap the event (or you can check out … proteins in human cells is an important finding. When gene therapies reached clinical trials in the late 1990's, …
Outreach
The USA Science and Engineering Festival is an opportunity to take part in hands-on genetics and genomics activities.
… Tree . The CRISPR Corner Are you familiar with the term “gene editing”? Gene editing is a hot topic of discussion and has many …
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… time, we have developed powerful new technologies for editing a human (or any) genomes? We may not yet have jet … called CRISPR was developed and has revolutionized genome editing. The scientists who developed CRISPR recognized that … bacteria and develop "bacterial scissors" for surgically editing any DNA in any organism. CRISPR has made genome …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in … of Genome Research , the researchers reported that the gene-editing technology known as CRISPR/Cas9 is six times more … A new role for zebrafish: larger scale gene function studies …
Research at NHGRI
The Metabolic Medicine Branch houses clinical and laboratory research programs that focus on the development of new therapies for patients with genetic disorders.
… Our investigators and their research teams develop gene addition therapy and gene editing approaches to treat metabolic disorders, study immune …