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Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… The Genomics, Environmental Factors and the Social Determinants of Cardiovascular Disease in … study is developing a community-based cohort and novel genomic science resource for defining the … genomic variation characteristic of African-Americans (AA) and the exposome of social determinants and environmental …
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… it encodes is not produced or does not function properly, and as a result, uncontrolled cell division may occur. Such …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… be thought of as an “on/off switch” to control when and where RNA molecules and proteins are made and as a … and cell types. The RNA and protein products of many genes serve to regulate the expression of other genes. Where, when, and how much a gene is expressed can also …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… have inherited mutations in certain cancer-susceptibility genes have a lifetime risk of cancer that is significantly …
Talking Glossary
La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y el entorno físico y social.
… Interacción genes-ambiente … La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y … La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data.
… cell fates or cell states. They use the gene expression and functional element data to construct gene regulatory … from one physiologic state to another. They derive and test predictions from the models, to determine the … data to understand what elements are controlling what genes, in what cell types. The ability to make accurate …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
… of canine genomics, sport hunting dogs are super athletes and terriers are plucky supermodels. National Human Genome … researchers reached this conclusion after identifying 59 genes or gene regions linked to canine athletics, including … flow and pain perception. What terriers lacked in sporty genes, they made up for in genes associated with physical …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National … effective than other techniques at homing in on target genes and inserting or deleting specific sequences. The study …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… than $28 million aimed at deciphering the language of how and when genes are turned on and off. These awards emanate from the recently launched … "There is a growing realization that the ways genes are regulated to work together can be important for … aims to develop new ways for understanding how the genes and switches in the genome fit together as networks. Such …