Search Results
Staff
Dr. James Inglese is an adjunct investigator in NHGRI's Metabolic Medicine Branch.
… High throughput technologies enable assays of biochemical, … an experimentally efficient and reproducible manner. These high throughput screening, or HTS, assays enable the investigation … James Inglese, high-throughput screening, large synthetic compound libraries, …
Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… DNA sequencing determines the order of the four chemical building … Sequencing DNA means determining the order of the four … the pairing also underlies the methods by which most DNA sequencing experiments are done. The human genome contains … (NHGRI) Genome Technology Program and its Advanced DNA Sequencing Technology awards. One of NHGRI's goals is to …
News Release
Researchers, clinicians, and computational biologists meet to consider future opportunities for NHGRI's Genome Sequencing Program.
… Human Genome Research Institute's (NHGRI) flagship Genome Sequencing Program (GSP) at a July 28 - 29 meeting in … The workshop, "Future Opportunities for Genome Sequencing and Beyond: A Planning Workshop for the National … significant projects that push the boundaries of genome sequencing technology applications and develop important data …
Research Funding
The Genome Sequencing Program uses genome sequencing to identify genes and genomic variants underlying human inherited disease.
… The Genome Sequencing Program is consists of the following centers … The NHGRI Genome Sequencing Program (GSP) has evolved from NIH's participation in the International Human Genome Sequencing Project (HGP). In addition to creating an … resources and tools. The specific activities of the Genome Sequencing Program since the end of the HGP reflect changes …
News Release
NHGRI-funded CSER investigators and colleagues point to need for greater evidence that DNA sequencing helps patients.
… In the nearly four years since its launch, the Clinical Sequencing Exploratory Research (CSER) program has made … disease; improved the analysis and interpretation of DNA sequencing results; and provided new insights into the … Maryland, for a one-day conference, Integrating Genomic Sequencing into Clinical Care: CSER and Beyond . The meeting …
News Release
NHGRI convened geneticists, biologists, clinicians, bioinformatics specialists and more to provide expert advice on the future of its Genome Sequencing Program.
… provide expert advice on the future of its flagship Genome Sequencing Program (GSP). … two-day meeting, titled, Future Opportunities for Genome Sequencing and Beyond: A Planning workshop for the National … clinic. In addition to the long-established Large-Scale Sequencing and Analysis Center (LSAC) program, the GSP now …
Talking Glossary
Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule.
… Nanopore DNA Sequencing … Nanopore DNA sequencing is a laboratory technique for determining the … Nanopore DNA sequencing is a laboratory technique for determining the … that cells use to develop and operate. Nanopore DNA sequencing involves reading the code of single DNA strands as …
Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… The NIH Intramural Sequencing Center (NISC) , established in 1997, is a … Institutes of Health (NIH) access to well established, high-throughput DNA sequencing, NISC works closely with NIH … NIH Intramural Sequencing Center … The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility …
Talking Glossary
The genome reference sequence provides a general framework and is not the DNA sequence of a single person.
News Release
A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional practices for validating DNA sequencing results.
… is challenging traditional practices for validating DNA sequencing results. The research suggests that newer, faster, "next-generation" DNA sequencing (NGS) methods are as accurate - and perhaps more accurate - than Sanger sequencing, a time-tested technique that is typically used to …