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TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), both parts of the … and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… severity of the disease. Learn more about your red blood cells to help you better understand these various approaches. … of treatments A variety of approaches target the blood stem cells to reduce your symptoms of sickle cell disease.  Gene … transplant In a bone marrow transplant , also called a stem cell transplant, your stem cells are replaced with new …
Educational Resources
The plasma membrane, also called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment.
… called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the … called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment. In bacterial and plant cells, a cell wall is attached to the plasma membrane on its …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… years. Now, a team headed by scientists at the National Human Genome Research Institute (NHGRI) has found a promising … presence is necessary for the generation of white blood cells called T follicular helper (TFH) cells in response to a viral infection. These TFH cells then …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… and Head of the Hematopoiesis Section at the National Human Genome Research Institute (NHGRI). NHGRI is one of the … degree from Colby College in 1976, a master's degree in Human Genetics from Rutgers in 1977 and a Ph.D. for his work … served on the Scientific Advisory Boards of the Center for Stem Cell and Regenerative Medicine, the National Disease …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… cell endometrial cancer (CCEC) tumors to date, National Human Genome Research Institute (NHGRI) researchers and their … NHGRI.  Dr. Bell and her team isolated DNA from tumor cells and from normal cells from patients with CCEC. Their goal was to identify …
Fact Sheet
Sickle cell disease resources for patients
… for a Research Study  U.S. Department of Health and Human Services (HHS)  Human Research Volunteer Informational Videos  U.S. Department of Health and Human Services (HHS)  NIH Clinical Research Trials and You – …
Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project developed patient-focused educational materials for the sickle cell community.
… change in the gene that produces hemoglobin, the red blood cells that carry oxygen throughout the body. In December …
Human Genome Project
Record and submit a short video, capturing your thoughts/concerns/excitement about the launch of the Human Genome Project.
… 1, 2020, marks the 30th anniversary of the launch of the Human Genome Project. NHGRI would like you to help us … feeling] about the launch of the Human Genome Project.  Francis Collins Eric Green  … When I first heard of the ambitious effort called the Human Genome Project, I was …  The Human Genome Project …
Fact Sheet
Gene therapy for sickle cell disease is available to you through FDA-approved therapies and through clinical trials.
…  Step 4: Preparation for stem cell collection (~90 days)  Gene therapy requires stem cells to be collected from your bone marrow or blood, taken … Step 5: Stem cell collection (~6–8 weeks) The stem cell collection … round occurs over two to three days. To collect your stem cells, you will: Be admitted to the hospital for 1 to 3 days. …