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Research at NHGRI
The Metabolic Medicine Branch houses clinical and laboratory research programs that focus on the development of new therapies for patients with genetic disorders.
… The Metabolic Medicine Branch (MMB) houses clinical and … The research conducted in the Metabolic Medicine Branch involves interconnected … gene addition therapy and gene editing approaches to treat metabolic disorders, study immune manifestations caused by … Metabolic Medicine Branch …
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… into four distinct molecular subtypes researchers with The Cancer Genome Atlas (TCGA) Network have found. In the study, published online July 23, 2014, in Nature , the scientists report that this discovery could … gastric cancer as a single disease, as has been done in the past, researchers will now be able to explore …
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… Genomics is transforming how we study, diagnose and treat cancer. … moving toward treating cancers not by where they are found in the body, but by how their genomes have changed? Cancer is caused by changes in your genome, but advances in DNA sequencing … blood cancer called acute lymphoblastic leukemia (or ALL) in 2003, when he was in his fourth year of medical school. …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified … potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease. They also discovered that, at the molecular …
Talking Glossary
El cáncer es una enfermedad en la que algunas células del cuerpo crecen fuera de control. Hay muchos tipos diferentes de cáncer, y cada uno comienza cuando una única célula adquiere un cambio genómico (o mutación) que le permite dividirse y multiplicarse sin control.
Genetic Disorders
Colon cancer is a malignant tumor of the large intestine that affects both men and women.
… Colon cancer, a malignant tumor of the large intestine, affects both men and women. In the United States, approximately 160,000 new cases of colorectal cancer are diagnosed each year. … tumor of the large intestine, affects both men and women. In the United States, approximately 160,000 new cases of …
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
… The Metabolic, Cardiovascular and Inflammatory Disease Genomics … Investigators focus, in particular, on diseases that are disproportionately … genomic initiatives, such as the Human Heredity and Health in Africa-H3Africa-project, this branch facilitates inclusion …
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… Investigators with The Cancer Genome Atlas (TCGA) Research Network have discovered … - with potentially important clinical implications - in head and neck cancers caused by infection with the human … (HPV). HPV is the most common sexually transmitted virus in the United States, and the number of HPV-related head and …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in 6 American men will develop prostate cancer during their … The prostate is a small gland shaped like a walnut that is in the center of a man's body within the pelvis. The prostate …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… For many cancer patients and their doctors, the deadliest enemy is … of cancer cells from the original tumor to other places in the body. In at least 90 percent of hard-tumor cancer deaths, the … of possible anti-metastasis compounds is based on in vitro procedures - basically, testing hundreds of …