Search Results
Educational Resources
A stem cell is a cell with the potential to form many of the different cell types found in the body.
… of the different cell types found in the body. When stem cells divide, they can form more stem cells or other cells that perform specialized functions. Embryonic stem …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… explain up to 12% of the differences between two people’s blood pressure. … National Institutes of Health researchers … as genomic loci , that appear to influence a person’s blood pressure. Results of the study also point to several … Genetics , is one of the largest such genomic studies of blood pressure to date, including data from over 1 million …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… modify the severity of the disease. Learn more about your red blood cells to help you better understand these various approaches. …
Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project developed patient-focused educational materials for the sickle cell community.
… by a change in the gene that produces hemoglobin, the red blood cells that carry oxygen throughout the body. In December …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… its make-up is different among cell types, even among cells that are similar. Investigators from two National Human … creating maps of what chromatin looks like in individual cells. They've combined several technologies, including DNA … have gained insights into how genomic information inside cells is controlled - literally turned on or off. The study …
Educational Resources
The plasma membrane, also called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment.
… called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the … called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment. In bacterial and plant cells, a cell wall is attached to the plasma membrane on its …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… But its presence is necessary for the generation of white blood cells called T follicular helper (TFH) cells in response to a … These TFH cells then interact with another type of white blood cell - called B cells - that actually produce the …
Fact Sheet
Sickle cell disease resources for patients
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… stem cell) and change it into different types of cells in the body. … Called induced pluripotent stem cells (iPSCs), this technique opens the doors to medical … a healthy person and the second set from a person with a blood disease called familial platelet disorder. Using skin …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… leg ulcers. These and other symptoms result when mutated red blood cells take a sickle shape, blocking blood flow and decreasing …