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Educational Resources
A stem cell is a cell with the potential to form many of the different cell types found in the body.
… Stem Cell … A stem cell is a cell with the potential to form many of the different cell types found in the body. … Cell, Mitosis … A stem cell is a cell with the potential to form many of the different cell …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to … Mitochondria are important components of nearly every cell in the body because they convert food and oxygen into … affect the immune system. Using a genomic technique called single-cell RNA sequencing, which analyzes gene activity in …
15 Ways Genomics Influences Our World
Genomics is establishing more robust methods for DNA-based forensic analyses.
… is establishing more robust methods for DNA-based forensic analyses. … Did you know that forensic analyses of DNA were being used well before the completion of … those detectives on TV and in the movies actually use DNA analyses to match a person to a crime or to determine the …
News Release
NIH will award nearly $80 million to support the establishment of the Mendelian Genomics Research Consortium and the development of novel methods and approaches that help researchers identify the genetic causes of single-gene diseases.
… that help researchers identify the genetic causes of single-gene diseases. Over 400 million people worldwide have … disorders generally thought to be caused by mutations in a single gene. The awards will be provided by the National … NIH funds new effort to discover genetic causes of single-gene disorders …
Educational Resources
Haploid is the quality of a cell or organism having a single set of chromosomes.
… Haploid is the quality of a cell or organism having a single set of chromosomes. … Haploid refers to the presence of a single set of chromosomes in an organism’s cells. Sexually … Haploid is the quality of a cell or organism having a single set of chromosomes. …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… complex that packages DNA into chromosomes in the cell - to better understand how the genome works. A better … Chromatin influences gene activity in a cell by controlling access to the genes and regulatory … with recent innovations in technologies to examine single cells. They labeled chromatin from thousands of cells, …
Educational Resources
The plasma membrane, also called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment.
… Plasma Membrane (Cell Membrane) … The plasma membrane, also called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment. … Organelle, Nuclear Membrane, Bacteria, Cell, Cell Membrane (Plasma Membrane) …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… that a transcription factor known as TCF1 (for T cell factor-1) is essential for the creation and persistence … TFH cells then interact with another type of white blood cell - called B cells - that actually produce the antibodies. … TCF1 deficiency causes "a severe defect" in the TFH cell response to viral infection, they concluded. "This …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… developed the breakthrough technique to return any adult cell to its earliest stage of development (a pluripotent stem cell) and change it into different types of cells in the body. … duplicated by subcloning. Subcloning is a technique where single cells are cultured individually and then grown into a …
Fact Sheet
Sickle cell disease resources for patients
… Education Project welcomes your feedback about the sickle cell disease gene therapy resources. Please email your … your general understanding of gene therapy for sickle cell disease. We encourage you to use these educational … What is Sickle Cell Disease?   National Institutes of Health (NIH)  About …