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News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… For many cancer patients and their doctors, the deadliest enemy is metastasis - the migration of cancer cells from the original tumor to other places in the body. In at least 90 percent of hard-tumor cancer … zebrafish as a live animal model of metastasis - offering cancer researchers a new, potentially more accurate way to …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Receiving a cancer diagnosis can feel like losing control of everything. In the wake of such a diagnosis, patients, family and friends … Will it spread? Sometimes doctors can offer answers, but in other cases they are elusive. Without information, the … its natural defenses, which can then lead to diseases like cancer," said Laura Elnitski, Ph.D., a senior investigator in …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… For a patient with cancer, two of the most important words in the oncologist's lexicon begin with the letter "r": … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no … do some patients stay in remission, while others see their cancer return? To get a better idea of who will be more …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and progression. … aggressive cancers, including prostate, endometrial, bladder, lung, head and neck, and gastric cancers. They also …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … A cancer-susceptibility gene is a gene that, when changed (or … cancer. Individuals who have inherited mutations in certain cancer-susceptibility genes have a lifetime risk …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid … Largest Study of Its Kind Endometrial cancer is the most commonly diagnosed gynecological cancer …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most … TCGA is jointly funded and managed by the National Cancer Institute (NCI) and the National Human Genome Research …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… How well cancer patients fare after chemotherapy can be affected by … Institutes of Health, and the University of Oxford in the United Kingdom. … Cancer patients were a little more likely to survive for five … years or more. Patients were a little more likely to die in less than five years after chemotherapy when they …