Search Results
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… chromosomes in the cell - to better understand how the genome works. A better understanding of chromatin will yield important insights into the genome's working parts and how those parts are managed. … access to the genes and regulatory proteins that make the genome work. Chemical tags that stick to the DNA impact …
Research Funding
The N​on-Coding Variants Program explores which variants in a region associated with a disease or trait cause the higher risk for the disease or trait
… of many people are sequenced, millions of sites in the genome differ among those people. Some of these genetic … of genes? A start to interpreting variation is a genome-wide association study (GWAS), in which the genomes of … a disease or trait are compared to find the chromosomal regions that affect the disease risk or trait. In these …
Educational Resources
A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome.
Genomics and Medicine
The NHGRI Genomic Medicine Working Group has compiled a list of interesting advances.
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… In 2003, an accurate and complete human genome sequence was finished and made available to scientists … and researchers two years ahead of the original Human Genome Project schedule and at a cost less than the original … effort to sequence the 3 billion DNA letters in the human genome is considered by many to be one of the most ambitious …
The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… Thirty years ago, today, the Human Genome Project (HGP) officially launched. I was there on the … been awarded one of the first center grants for the Human Genome Project by the then-named National Center for Human Genome Research. For that grant, I led a small research group …
The Genomics Landscape
In the July 2020 edition of The Genomics Landscape, NHGRI Director Eric Green recalls the White House event announcing the draft human genome sequence.
… announce the completion of a draft sequence of the human genome. The ceremony took place in the East Room of the White … gathered to celebrate a major milestone for the Human Genome Project. This historic landmark for biomedical … covered about 99 percent of the genome's gene-containing regions and had an accuracy of 99.99 percent. The draft human …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
… Late last month, I attended the annual Advances in Genome Biology and Technology (AGBT)  general meeting. The … – in one way or another – busily involved in the Human Genome Project. Having now attended all 21 AGBT general … will mark the 30th anniversary of the launch of the Human Genome Project (HGP). To commemorate this historic …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… Your genome is the operating manual containing all the … And it’s unique to you. The more you know about your genome and how it works, the more you'll understand your own … in the highly structured and tightly packed nature of the genome. … worth much until someone reads it. The same goes for your genome. The letters of your genome combine in different ways …
The Genomics Landscape
In the April 2020 edition of The Genomics Landscape, NHGRI Director Eric Green provides an update on the final stage of the Genomics2020 strategic planning process; the NIH website for COVID-19 information, the Gene documentary debut on PBS and more.
… up to the 30th anniversary of the launch of the Human Genome Project in October 2020. The first four such oral … of strategic planning that dates back to the Human Genome Project. These efforts have proven extremely valuable … . NHGRI plans to release the draft 2020 strategic plan on genome.gov on April 15. At that time, we will be engaging …