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Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… DNA sequencing determines the order of the four chemical building … Sequencing DNA means determining the order of the four chemical building blocks - called "bases" - that … which most DNA sequencing experiments are done. The human genome contains about 3 billion base pairs that spell out the …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… Comparative genomics is a field of biological research in which researchers use a variety of tools to compare the complete genome sequences of different species. By carefully comparing … is, preserved in many different organisms over millions of years - is an important step toward understanding the …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… serve as President Biden’s science advisor and director of the White House Office of Science and Technology Policy (OSTP), and Dr. Alondra … Vision — Generating and analyzing a complete human genome sequence will be routine for any research laboratory, …   Maximize the usability of genomics for all members of the public, including the …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… Why was it so difficult to fully complete the human genome sequence? The Human Genome Project ended in 2003, but … had not yet determined every last base (or letter) of the human genome sequence. Instead, they had only completed about 92% of the sequence at that time. Why did they stop there? A …
Research Funding
GS-IT provides sequence analysis tools and software to scientists who rely on genomics in their research.
… The GS-IT strategy is to invest in existing tools of known utility to make them robust, reliable, documented, … in the cloud or interactive visualization to ease the path of researchers who are seeking tools they can successfully … McCarroll Scripps Institute: Ali Torkamani University of Southern California: Ting Chen, Ewa Deelman, Jim Knowles …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… Happy New Year! The arrival of 2018 brings great anticipation about what this year might bring in terms of amazing genomic advances. Before staring too long into … Science  and Nature . While Science's  Breakthrough of the Year for 2017  is the cosmic merger of two neutron …
News Release
NHGRI will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases.
… The National Institutes of Health will fund a set of genome sequencing and analysis centers whose research will focus on … The National Human Genome Research Institute (NHGRI), part of NIH, today … Exploring the Genome's Role in Disease … NIH genome sequencing program targets the genomic bases of common, rare disease …
The Genomics Landscape
In the July 2019 edition of The Genomics Landscape, NHGRI Director Eric Green reflects on the milestones of the Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT) Program as it reaches completion.
… experts, healthcare professionals, and interested members of the public. Specifically, the discussions will focus on … The Genome: Unlocking Life's Code  exhibition is currently … Redding, CA After : January 17 – April 12, 2020 Museum of Science & History Jacksonville, FL …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… Techniques to modify DNA in the genome have existed for several decades, but the conversation about the science and ethics of genome editing has grown louder due to faster, cheaper, and … While the popular media tends to focus on the potential use of genome editing in humans, the main application of this …
The Genomics Landscape
In the October 2019 edition of The Genomics Landscape, NHGRI Director Eric Green focuses on recent efforts to make the human genome reference sequence useful to basic and clinical researchers and how increasing the representation of human genomic variation will remain key components of NHGRI’s Human Genome Reference Program.
… I had the pleasure of giving the opening talk at the fourth annual International … participants understand the prevalence and basis of genetic diseases in their nations and the associated … health challenges, is sponsored by NHGRI; a collection of other NIH institutes and centers; and the Foundation for …