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News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no detectable cancer. But, unfortunately, some patients will hear the word …
Event
NHGRI will host a TiDHE ancillary event for trainees and early-stage career investigators at the 2022 ASHG Annual Meeting on October 27, 2022.
… (NHGRI) will host an ancillary event for trainees and early-stage career investigators,  "NHGRI Building a Diverse Workforce: Listening to the Voices of Trainees and Early-Stage Scientists," at the 2022 ASHG Annual Meeting. … Diverse Workforce: Listening to the Voices of Trainees and Early-Stage Scientists …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid … The study was published May 9, 2017, in the journal Cancer . …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer. Individuals who have inherited mutations in certain …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical … test that can be used to diagnose a variety of cancers at early stages, when treatments can be most effective. The …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. Knowledge of these genomic changes may expand the … TCGA is jointly funded and managed by the National Cancer Institute (NCI) and the National Human Genome Research …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… How well cancer patients fare after chemotherapy can be affected by … Cancer patients were a little more likely to survive for five … out to see if the impact of social interaction extended to cancer patients undergoing chemotherapy. Joining this … role in disease outcomes," said Dr. Koehly. "As cancer care moves more towards targeted therapies based on …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and progression. … and somatic (body cell) mutations that contribute to cancer susceptibility syndromes and to the development of … also study the relationship between genetic variation and cancer progression and pursue the discovery of both inherited …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… A repurposed cancer drug appears to reduce the severity of lesions and … "The results were so encouraging that we ended the study early, so we can begin the next one to determine the … goal in using the drug was very different from its use in cancer therapy. In cancer, the objective is to eliminate all …