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Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… in many genes themselves play a role, small variations in DNA sequences near genes that control when and how much a … crossbred several strains of mice and examined regulatory DNA and gene activity in brain and other tissue. They found … Medicine, NHGRI; Andrea Beckel-Mitchener, Ph.D., chief, Functional Neurogenomics Program, Division of Neuroscience …
Educational Resources
DNA fingerprinting is a laboratory technique used to establish a link between biological evidence and a suspect in a criminal investigation.
… DNA Fingerprinting … DNA fingerprinting is a laboratory technique used to … DNA Fingerprinting, Criminal Investigation, Forensics, DNA Sequence, Paternity Test … DNA fingerprinting is a laboratory technique used to … on the nucleotide sequences of certain regions of human DNA that are unique to individuals. DNA fingerprinting is …
News Release
The newly launched Impact of Genomic Variation on Function (IGVF) consortium to include 30 U.S. sites.
… alternate orders of the As, Cs, Gs and Ts that make up our DNA — combined with the environment and lifestyle ultimately … function. The IGVF consortium includes five components: Functional Characterization Centers, Regulatory Network …
Educational Resources
Non-coding DNA corresponds to the portions of an organism’s genome that do not code for amino acids, the building blocks of proteins.
… Non-Coding DNA … Non-coding DNA corresponds to the portions of an organism’s genome that … DNA Sequence, Gene Expression, Chromosome, Non-coding DNA, Junk DNA, Genetic Code … proteins. Some non-coding DNA sequences are known to serve functional roles, such as in the regulation of gene …
For Teachers
Lesson plan based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity.
… This lesson is based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity. … under the Molecules of Genetics  section of the DNA from the Beginning  website. The science behind each … students with the Molecules of Genetics section of the DNA from the Beginning  website. It is intended for middle …
Profile
In a conversation, Dr. Elise Feingold reflects on her path to NHGRI, describes her experience leading the ENCODE program and shares advice for those considering different scientific careers.
… particularly proud of? Feingold: The Encyclopedia of DNA Elements (ENCODE) program is the one I feel most proud of, … at NHGRI, Elise Feingold, Ph.D. , led the Encyclopedia of DNA Elements (ENCODE) project , a monumental effort that sought to decipher and catalog all of the functional elements encoded in the human genome. She even …
Outreach
National DNA Day commemorates the successful completion of the Human Genome Project in 2003 and the discovery of DNA's double helix in 1953.
… National DNA Day is a unique day when students, teachers and the … of the Human Genome Project in 2003 and the discovery of DNA's double helix in 1953. … National DNA Day commemorates the successful completion of the Human Genome Project in 2003 and the discovery of DNA's double helix in 1953. The National Human Genome …
Event
The Encyclopedia of DNA Elements (ENCODE) Consortium presented a half-day workshop on the accessibility & utilization of ENCODE data.
… The Encyclopedia of DNA Elements (ENCODE) held a workshop as an ancillary event to … The Encyclopedia of DNA Elements (ENCODE) Consortium presented a half-day workshop on … The Encyclopedia of DNA Elements (ENCODE) Consortium presented a half-day workshop on …
Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique. DNA, along with the instructions it contains, is passed from … In organisms called eukaryotes, DNA is found inside a special area of the cell called the …
Talking Glossary
Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule.
… Nanopore DNA Sequencing … Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. … Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. The sequence of the bases (often referred to by …