Search Results
Research at NHGRI
The goal of our Caregiving Study is to understand how caregivers manage the demands of caring for a loved one with a long-term health condition and how social relationships affect caregivers' ability to cope.
… on caregivers’ health and well-being. Our Caregiving Study explores the impact of caregiver stress over time and … ability to cope with caregiving demands. The Caregiving Study focuses on the following diagnoses: Inborn errors of … 2024 Caregiving Study Newsletter 2023 Caregiving Study Newsletter 2022 …
Clinical Research
A Longitudinal Natural History Study of Children with Mitochondrial Disease (at the NIH Clinical Center).
… The Metabolism, Infection and Immunity (MINI) Study is a longitudinal natural history study at the National Institutes of Health (NIH) that  aims … The main goal of our study is to understand the relationship between infection and … we do provide advice and care for people enrolled in our study, we are not able to take over the long-term care of …
Policies and Guidance
A webpage with information and associated FAQs that describe various expectations for data sharing that are specific to NHGRI-supported studies.
… How to Register Controlled-Access Studies  Study registration in dbGaP is required for large-scale human … process outlined in How to Register and Submit Your Study in dbGaP  (Steps 1 – 6) to register your study in dbGaP. Next, see the AnVIL Submission Guide for …
News Release
By considering mixed genetic lineages, NHGRI researchers demonstrated that previously inferred links between a genomic variant that helps digest lactose and traits such as a person’s height and cholesterol level may not be valid.
… NIH study finds that failing to account for mixed genetic … mixed genetic lineages, researchers at the National Human Genome Research Institute (NHGRI), part of the National … as admixture. As such, the results from previous genome-wide association studies that do not account for admixture in …
News Release
Researchers show critical association between diabetes and previously unlinked ZRANB3 gene.
… Researchers show critical association between diabetes and previously unlinked ZRANB3 … Mellitus study, the single largest diabetes genomic association study conducted on the continent. Using the … populations. The work was funded by the National Human Genome Research Institute (NHGRI), the National Institute of …
News Release
In a new large-scale genetic analysis, National Institutes of Health (NIH) scientists have found set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type 2 diabetes.
… NIH study identifies new molecules involved in diabetes. … of pancreatic islets is important for human health. The study, led in part by scientists at the National Human Genome Research Institute (NHGRI), part of the National …
Staff
Dr. Oleg Shchelochkov is Director of NHGRI Clinical and Laboratory Residencies and Fellowships, and an Associate Investigator in the Office of the Clinical Director.
… to the studies of propionic acidemia. This protocol-based study enabled novel insights into the spectrum of clinical …
News Release
A new study highlights how genomic mutations that cause mitochondrial disease may also compromise affected people's immune response.
… A new study highlights how genomic mutations that cause … M.D., senior author and investigator at the National Human Genome Research Institute. Related Resources Cytochrome c … Training docs to be researchers, too... The NIH MINI Study: Metabolism, Infection and Immunity in Inborn Errors of …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… gene therapy for humans. Researchers at the National Human Genome Research Institute (NHGRI), part of NIH, published … gene therapy applications. But one prior study did find an association between AAV and the occurrence of liver cancer. … additional experiments to detect where in the mouse genome the AAV vector delivered the corrected gene and how …
News Release
Using a virtual reality buffet, researchers studied the hundreds of small decisions mothers make while selecting food for their children.
… to make healthier choices. The findings, by National Human Genome Research Institute (NHGRI) researchers, were published … Stronger Messages Means Smaller Portions "In this study, we found that individuals who received the strongest … most effective ways to deliver genomic information. In the study, 221 overweight or obese mothers entered a virtual …