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News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Receiving a cancer diagnosis can feel like losing control of everything. In the wake of such a diagnosis, patients, family and friends … Will it spread? Sometimes doctors can offer answers, but in other cases they are elusive. Without information, the … How tumors differ from each other - either in different organs or within the same organ - can yield …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… Over the years, domestic dogs have figured in medical breakthroughs, whether by mushing across Alaska to … our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no … rules will help doctors better understand what mutations - changes to the cancer cell's DNA - may lead to relapse. In …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because of the similarities in the dog and human immune systems - has baffled researchers … Canine transmissible venereal tumor, or CTVT, spreads when cancer cells move from one dog to the other during sexual …
News Release
NHGRI has selected Charles Venditti, M.D., Ph.D., as chief of its Metabolic Medicine Branch within the Institute’s Intramural Research Program. In this role, he will provide leadership and guidance on research into genetic diseases that disrupt metabolism.
… selected Charles P. Venditti, M.D., Ph.D., as chief of its Metabolic Medicine Branch within the Institute’s Intramural Research Program. In this role, he will provide leadership and guidance on … in the basic, translational and clinical aspects of metabolic diseases,” said Charles Rotimi, Ph.D., NHGRI …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … and their collaborators have identified mutations in the TAF1 gene. They've also demonstrated that the mutation … build a knowledge base to decipher the fundamental genomic changes that drive these cancers." Dr. Bell and her team …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … confirmed that PTCs are driven primarily by mutations in one of two cancer-associated genes: BRAF (and a particular …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… A repurposed cancer drug appears to reduce the severity of lesions and … disease. The drug, miransertib, was well tolerated, even in children, according to a National Institutes of Health … and collaborators published the findings Feb. 21, 2019, in the American Journal of Human Genetics . …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… How well cancer patients fare after chemotherapy can be affected by … Institutes of Health, and the University of Oxford in the United Kingdom. … Cancer patients were a little more likely to survive for five … years or more. Patients were a little more likely to die in less than five years after chemotherapy when they …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and progression. … acquired and accumulate over time. Some of these genomic changes drive tumor initiation, growth and metastases, while …