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Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… The NIH Intramural Sequencing Center (NISC) , established in 1997, is a … facility that emphasizes the generation and analysis of DNA sequence. In addition to providing investigators at the … Health (NIH) access to well established, high-throughput DNA sequencing, NISC works closely with NIH collaborators to …
Research Funding
Funded in 2016 to harmonize, access, and analyze the data produced by the sequencing centers.
… The Genome Sequencing Program Analysis Centers (GSPACs) were funded in … to harmonize, access, and analyze the data produced by the sequencing centers. The GSPACs undertake novel, … Genome Sequencing Program Analysis Centers … to harmonize, access, and analyze the data produced by the sequencing centers. …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… Identifying DNA sequences that have been "conserved" - that is, preserved … biology of living things have changed over time. As DNA sequencing technology becomes more powerful and less expensive, … all living creatures, both plants and animals, consist of DNA (deoxyribonucleic acid), the chemical chain that includes …
Educational Resources
Cloning is the process of making identical copies of an organism, cell, or DNA sequence.
… of making identical copies of an organism, cell, or DNA sequence. … DNA Sequence, Ethics, Cloning … or virtually identical, copies of an organism, cell or DNA sequence. The phrase “molecular cloning” typically refers to isolating and copying a particular DNA segment of interest for further study. …
Educational Resources
Mitochondrial DNA is the small circular chromosome found inside mitochondria.
… Mitochondrial DNA … Mitochondrial DNA is the small circular chromosome found inside … Mitochondrial DNA, Mitochondria, Cell Biology, Inheritance … Mitochondrial DNA is the circular chromosome found inside the cellular … inherit mitochondria — and as a result mitochondrial DNA — from their mother. …
Educational Resources
A genetic marker is a DNA sequence with a known physical location on a chromosome.
… A genetic marker is a DNA sequence with a known physical location on a chromosome. … Genetic Marker, DNA Sequence, Chromosome, Genetic Disease, Inheritance … A genetic marker is a DNA sequence with a known physical location on a chromosome. … help link an inherited disease with the responsible gene. DNA segments close to each other on a chromosome tend to be …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… a public research consortium named the Encyclopedia of DNA Elements (ENCODE) in September 2003 to carry out a … genome was announced by the International Human Genome Sequencing Consortium ( Finishing the euchromatic sequence of … and new methods to identify functional sequences in DNA. On July 23-24, 2002, the NHGRI organized a workshop, …
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, Bioengineering, DNA Sequencing, Base Pair, Chromosomes … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells …
Event
The Advances in Genomic Technology Development meeting and Genome Technology Forum were hosted by the National Human Genome Research Institute (NHGRI) Technology Development Coordinating Center (TDCC) at The Jackson Laboratory in Farmington, CT from June 10-13, 2024.
… The Advances in Genomic Technology Development (AGTD) meeting was hosted by the … key opportunities and challenges for advanced genomic sequencing and synthesis technologies, and novel genomic … functions and technologies for making and sequencing DNA and RNA. Recordings of the lectures from the Genome …
Event
The Advances in Genomic Technology Development (AGTD) 2022 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) from July 12-14, 2022 at The Jackson Laboratory (Farmington, CT).
… Methods for Multi-omic Analysis of Chromatin Conformation, DNA Methylation, and Protein-DNA Binding Jesse Dixon, M.D. … Institute for Biological Studies 9:25 a.m. AVATAR: Novel Technology for Highly Parallel Analysis of Variation in … 2:00 p.m. Panel Discussion 2:20 p.m. Coffee Break New Sequencing Technology Session Moderators: Sukanya …