Search Results
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… positional cloning of mib, a gene in the Notch pathway in zebrafish. Mutations in mib result in increased neural … to neurons during embryonic development, leading to the zebrafish mind bomb phenotype. In a collaborative effort in … lab further investigated the expression of menin in mouse, zebrafish and drosophila development, and they also …
Staff
Dr. Brian Brooks is an adjunct investigator in NHGRI's Center for Precision Health Research.
… Brooks BP. Aldh7a1 regulates eye and limb development in zebrafish. PLoS ONE , 9:e101782. 2014. [ PubMed ] Johnston … A, Brooks BP. Nlz1 is required for cilia formation in zebrafish embryogenesis. Dev Biol, 406:203-211. 2015. [ …
News Release
NIH researchers have developed and released an innovative software tool, called Verso, to assemble truly complete (i.e., gapless) genome sequences from a variety of species. The software makes the process of assembling complete genome sequences more affordable and accessible.
… commonly used in research, such as mice, fruit flies and zebrafish, improving their usefulness to scientists. …
Research Funding
​The Undiagnosed Diseases Network accelerates discovery and innovation in how we diagnose and treat patients with previously undiagnosed diseases.
… and a new Model Organisms Screening Center increasing the zebrafish modeling capacity and adding C. elegans  as a new …
Educational Resources
An animal model is a non-human species used in medical research because it can mimic aspects of a disease found in humans.
… disease found in humans. Animal models (e.g., mice, rats, zebrafish and others) are sufficiently like humans in their …
Policy Issues
Genome editing is currently being applied to research on cancer, mental health, rare diseases, and many other disease areas.
… the petri dish and in nonhuman organisms such as mice or zebrafish. Researchers rely on genome editing tools as a way …
News Release
NHGRI researchers will present four platform talks and 55 posters to highlight the institute's diverse portfolio at the 65th annual meeting of ASHG.
… (Metabolic Disorders) *2271T. Oleg Schelochkov: A Zebrafish Knockout of Argininosuccinate Lyase Separates … and Polygenic Disorders) 1147F. Katherine Schaffer: Using zebrafish to model the role of GEMIN5 in neurological …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… experiments using cell lines and model organisms such as zebrafish to identify the role of genomic variants in SEMA4D …
News Release
NIH researchers researchers and collaborators have gained some key insights into the biological inner-workings of regrowing a body, the evolution of aging and a unique method to dispose of aging cells, by studying the genomes of a hermit crab (Hydractinia symbiolongicarpus).
… damaged liver. Some other animals, such as salamanders and zebrafish, can replace entire limbs and replenish a variety …
News Release
UDN expands the footprint of the network with a new metabolomics core and increased model organism capabilities.
… Ph.D., and Tim Schedl, Ph.D.), increasing the zebrafish modeling capacity and adding C. elegans as a new …