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Educational Resources
The microbiome is a term used to describe the specific collection of microorganisms (such as fungi, bacteria and viruses) that exist in a particular environment.
… Microbiome Project, Microbe, Microorganism, Bacteria, Virus, Genetic Material …
Educational Resources
An antibody is a protein component of the immune system that circulates in the blood, recognizes foreign substances like bacteria and viruses, and neutralizes them.
… Immune System, Bacteria, Virus, Blood, Circulation, Disease, Antigen …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… Gene Expression … Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule. … Gene expression is the process by which the information … activity of a gene product or observing a phenotype associated with a gene. …
News Release
A team from the NIH has surmounted a major obstacle to testing potential drug therapies for a rare, genetic condition called Gaucher disease.
… is an inherited condition caused by alterations in the GBA gene. It affects one in every 50,000 to 100,000 people, but … Gaucher disease, drug therapy for Gaucher disease, Ellen Sidransky Ph.D., GBA gene alterations, glucocerebroside accumulation …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… Understanding more about diseases caused by a single gene (using genetics) and complex diseases caused by multiple … the search for variations in multiple genes that are associated with variability in drug response. Since … and will be clones of the common ancestor bacterial cell. Gene cloning involves manipulations to make multiple …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in … of Genome Research , the researchers reported that the gene-editing technology known as CRISPR/Cas9 is six times … "It was shown about a year ago that CRISPR can knock out a gene quickly," said Shawn Burgess, Ph.D., a senior …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an … A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an … frequent cancer screens. There are also many gene variants associated with a small increase in risk. In some cases, …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… in the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene … significant problem, as the vast majority of disease-associated variants found using GWAS lie outside of …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
… reached this conclusion after identifying 59 genes or gene regions linked to canine athletics, including those with … terriers lacked in sporty genes, they made up for in genes associated with physical attributes such as their trademark … at agility events. ROBO1 gene has been suggested to be associated with the ability to learn. They also homed in on …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… awards emanate from the recently launched Genomics of Gene Regulation (GGR) program of the National Human Genome … disease." With these new grants, researchers will study gene networks and pathways in different systems in the body, … The resulting insights into the mechanisms controlling gene expression may ultimately lead to new avenues for …