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News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid … The study was published May 9, 2017, in the journal Cancer . …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … primary federal agency conducting and supporting basic, clinical, and translational medical research, and is …
Event
On October 10, 2024, NHGRI hosted a pre-application webinar for the Population Genomic Screening in Primary Care NOFOs. The purpose of these NOFOs is to implement and evaluate a pilot program of population genomic screening for common, actionable genomic conditions in a primary care setting.
… webinar for the Population Genomic Screening in Primary Care NOFOs: RFA-HG-24-021 , RFA-HG-24-022 , and RFA-HG-24-023 … for common, actionable genomic conditions in a primary care setting. … Population Genomic Screening in Primary Care Pre-Application Webinar … webinar for the Population Genomic Screening in Primary Care NOFOs. The purpose of these NOFOs is to implement and …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… How well cancer patients fare after chemotherapy can be affected by … Cancer patients were a little more likely to survive for five … out to see if the impact of social interaction extended to cancer patients undergoing chemotherapy. Joining this … role in disease outcomes," said Dr. Koehly. "As cancer care moves more towards targeted therapies based on genomic …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. Knowledge of these genomic changes may expand the … primary federal agency conducting and supporting basic, clinical, and translational medical research, and is …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… A repurposed cancer drug appears to reduce the severity of lesions and … It affects fewer than 500 individuals in the world. Clinical trials participant Jerry DeVries (right) receives … goal in using the drug was very different from its use in cancer therapy. In cancer, the objective is to eliminate all …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and progression. … and somatic (body cell) mutations that contribute to cancer susceptibility syndromes and to the development of … also study the relationship between genetic variation and cancer progression and pursue the discovery of both inherited …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical … primary federal agency conducting and supporting basic, clinical and translational medical research, and is …
News Release
Clinical geneticist to lead NHGRI’s clinical genomics research efforts
… Clinical geneticist to lead NHGRI’s clinical genomics research efforts … Solomon, M.D., to lead the institute’s intramural Clinical Research Program , which provides oversight and … in both fundamental genomics research and patient care. I am thrilled to welcome him to the NHGRI leadership …
Event
The Excellence in Clinical Research Seminar Series is designed to facilitate clinical research in the rare disease space with a focus on aspects of regulatory medicine and clinical trials in Mendelian disorders.
… The Excellence in Clinical Research Seminar Series is designed to facilitate clinical research in the rare disease space with a focus on regulatory medicine and clinical trials in Mendelian disorders. The series will … Excellence in Clinical Research Seminar Series …