Search Results
For Health Professionals
The ISCC-PEG Pharmacogenomics (PGx) Project Group has developed peer-reviewed online education for healthcare practitioners to advance pharmacogenomics in clinical practice.
… evidence-based pharmacogenomic resources from the Food and Drug Administration (FDA), the Clinical Pharmacogenetics … safety of psychiatric medications as well as the impact of drug-drug interactions (phenoconversion) through case-based …
Genetic Disorders
Familial hypercholesterolemia is an inherited condition causing increased low density lipoprotein cholesterol at birth and heart attacks at an early age.
… lose weight, may also help in lowering cholesterol levels. Drug therapy is usually necessary in combination with diet, … their significantly elevated levels of cholesterol. Often drug therapies are not sufficient to lower LDL cholesterol …
News Release
NHGRI participated in a science communications contest called the Three-Minute Talk. NHGRI's Ryan Johnson came away with a first place win.
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… may play a major role in the development of cancer drug resistance. …
News Release
When Dr. Ellen Sidransky, 2019 winner of the Jay Van Andel Award, looks into a rare disease, she finds a window to take the lead in Parkinson's research.
… isn't stopping any time soon. She is working on a drug for Parkinson's disease. Current drugs only treat the … symptoms, but Sidransky hopes to find a disease stopping drug. The Jay Van Andel Award for Outstanding Achievement in …
Research at NHGRI
CRGGH develops a comprehensive staff and training program that uses genomic approaches to study human health and to reduce/eliminate health disparities.
… and so on — it's pretty clear that at the level of drug metabolising enzymes, genes don't align themselves in a … for example, may carry different copies of important drug metabolising enzymes, and similar observations are true …
Staff
Dr. Sean Conlan is an associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.​
News Release
Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from harmful DNA viruses, strengthening the plant's protections.
Educational Resources
Single nucleotide polymorphisms (SNPs) are a type of polymorphism involving variation of a single base pair.
… if and how SNPs in a genome influence health, disease, drug response and other traits. …
The Genomics Landscape
In the June 2, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the new and improved Talking Glossary of Genomic and Genetic Terms - one of the premier educational resources offered by NHGRI, and it aims to help users better understand the basics of genomics and genetics.
… in tracking hospital-acquired infections of multi-drug-resistant organisms. Most recently, Julie has also been …