Search Results
Talking Glossary
Un gen de susceptibilidad al cáncer es un gen que, cuando cambia (o muta) confiere a la persona un mayor riesgo de desarrollar cáncer.
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
… Prostate Cancer … Prostate cancer is a disease characterized by uncontrolled cell growth … Cancer, Cell, Mitosis, Mutation … Prostate cancer is a disease characterized by uncontrolled cell growth … which is part of the male reproductive system. Prostate cancer generally affects men over the age of 50. It is …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… from over 10,000 tumors representing 33 types of cancer. … Francis S. Collins, M.D., Ph.D. "This analysis provides cancer researchers with unprecedented understanding of how, … informed clinical trials and future treatments." The Pan-Cancer Atlas, published as a collection of 27 papers across a …
News Release
NHGRI researchers have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.
… history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. Since 2012, Laura Koehly, … family trees associated with heart disease, diabetes, breast cancer and colorectal cancer. Definitions of each … history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
…  After more than a decade, The Cancer Genome Atlas (TCGA) program is drawing to an end. A … initiated and supported by NHGRI and the National Cancer Institute (NCI), with over $300 million in total … mission to catalog the genomic changes underlying multiple cancer types. Ambitious in scope from the beginning, TCGA was …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research … More information on TCGA can be found on NCI’s The Cancer Genome Atlas Program website . The Cancer Genome Atlas … Genome Atlas publishes results for bile duct, uterine and breast cancer  (2017)  TCGA study identifies genomic …
Staff
Dr. Bell is a senior investigator at the National Human Genome Research Institute's Cancer Genetics and Comparative Genomics Branch.
… She conducted her postdoctoral training at Fox Chase Cancer Center, Philadelphia, before joining Harvard Medical … on the fine-mapping of genomic deletions in ovarian cancer and in malignant mesothelioma as a means to home in on … the dramatic clinical responses of non-small cell lung cancer patients to gefitinib, a small molecule inhibitor of …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… switch from a different genetic neighborhood, turning on a cancer-growth gene. The research team was led by Bradley E. … in energy production, seemed to have no relevance to cancer. Dr. Bernstein and his colleagues found that when the IDH gene was mutated, particular portions of the cancer cells' DNA became studded with chemical tags called …
Staff
Dr. Lawrence Brody is a senior investigator in NHGRI's Social and Behavioral Research Branch and director of NHGRI's Division of Genomics and Society.
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… in normal metabolic pathways and cause disorders such as cancer and birth defects. His laboratory focuses on … a disease; variants of this type, such as those in known breast cancer-linked genes, are of great medical importance. … or BRCA2 mutations have a higher risk of developing both breast and ovarian cancer than women without such mutations. …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify … a wide array of training opportunities for scientists early in their careers . The NIH is dedicated to building a …