Search Results
News Release
Two grants will support studies on genomic literacy among Africans relating to research conducted in Africa by African investigators.
… Two grants totaling more than $300,000 will support studies on … in Africa by African investigators. The three-year grants are part of the Human Heredity and Health in Africa … a project to determine Ethiopians' understanding of gene-environment interactions, with a goal of also increasing …
About NHGRI
NHGRI's Initial Review Group provides first-level peer review of grant applications.
… Peer Review Grant Applications, Genomics Grants, NHGRI Budget, Center For Scientific Review, Research Training Grants In Genomics …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data.
… in the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene regulatory network models, taking advantage of the …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an … A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an … A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… of Health (NIH) researchers have demonstrated in mice that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1 (NPC1). The gene therapy involved inserting a functional copy of the NPC1 … has no cure. The disease occurs when a faulty housekeeping gene fails to remove cell waste, like lipids and cholesterol. …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
… reached this conclusion after identifying 59 genes or gene regions linked to canine athletics, including those with roles in endurance, heart function, blood flow and pain perception. What terriers … researchers have identified about 200 germline mutations - gene variants that can be passed on to subsequent generations …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… in understanding the elevated cancer risk associated with gene therapy. They conducted research on mice with a rare … humans, hoping their findings may eventually help improve gene therapy for humans. Researchers at the National Human … "Effective and safe gene therapies have the potential to dramatically reverse …
News Release
An expert panel from the Clinical Genome Resource (ClinGen) has critically reevaluated the scientific evidence for all 17 reported genes, disputing nine of the genes and revealing only three of the genes to be definitively associated with the most common form of the disease.
… reporting to physicians. Published papers reporting gene-disease associations vary widely in their study design … the scientific evidence from research papers to place gene-disease relationships into “definitive,” “strong,” … for the clinical genomics community regarding which gene-disease pairs have sufficient evidence to be used …
Fact Sheet
Understanding gene therapy for sickle cell disease
… Now, researchers are developing new and emerging gene therapies to treat sickle cell disease. To help navigate … for the Democratizing Education for Sickle Cell Disease Gene Therapy Project, which is led by NHGRI in partnership … welcomes your feedback about the sickle cell disease gene therapy resources. Please email your comments or …
Profile
Dr. Pavan looks back on his career at NHGRI, highlights pivotal moments and shares his future plans in artistic woodworking and community mediation.
… to go for a university job where I would have to write grants and teach on top of doing science. When NHGRI was … were supported so I didn't have to worry about writing grants. I could really focus on training people and doing … transformative discoveries are made. We would identify a gene from a screen or from observing a trait in an animal …