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An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because … Canine transmissible venereal tumor, or CTVT, spreads when cancer cells move from one dog to the other during sexual contact, without the help of a … in the journal Genome Research . "We figured out which genes the tumor modified so that it could escape the host …
Educational Resources
A candidate gene is a gene whose chromosomal location is associated with a particular disease or other phenotype.
… Genes, Chromosome, Phenotype, Traits, Disease, Linkage … The term candidate gene refers to a gene that is believed to be related to a particular trait, such as a disease or a …
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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … primarily by mutations in one of two cancer-associated genes: BRAF (and a particular mutation, V600E ) or RAS . The …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. Knowledge of these genomic changes may expand the … activity in 62 percent of the samples. The affected genes are oncogenes, or genes that have the potential to …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… How well cancer patients fare after chemotherapy can be affected by … with other patients during treatment, according to a new study by researchers at the National Human Genome … the difference occurred, but hypothesize that it may be related to stress response. "When you're stressed, stress …
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… of a trait that results from the interplay between genes and the environment. … Genes, Environmental Factors, Genetics, DNA … Gene–environment interaction refers to the interplay of genes (and, more broadly, genome … of a trait that results from the interplay between genes and the environment. …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… A repurposed cancer drug appears to reduce the severity of lesions and … was well tolerated, even in children, according to a National Institutes of Health study that sought only to … we ended the study early, so we can begin the next one to determine the potential of miransertib for treating this …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… large numbers of genotypes (an individual's collection of genes). Until now, it has been difficult for researchers to re-contact individuals with genotypes of interest and investigate the health consequences of their genes and gene variants. … will allow them to recall genotyped people and examine the genes and gene variants' influence on their phenotypes, an …
Educational Resources
A gene pool is the total genetic diversity found within a population or a species.
… Genetic Diversity, Genes, Extinction, Population Genetics … A gene pool refers to the combination of all the genes (including alleles) … pool has extensive genomic diversity and is better able to withstand environmental challenges. Inbreeding contributes …
Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… Genetic Disease, Genetic Disorder, Gene Mutation, Cancer Treatment, Healthcare … Gene therapy is a technique that uses a gene(s) to treat, prevent or cure a disease or medical disorder. …