Search Results
News Release
NIH recently awarded approximately $6.8 million in grants to several research teams to study the biology of rare and undiagnosed diseases.
… two new research centers, including a Model Organisms Screening Center and a Metabolomics Core, as part of the NIH … addition to two DNA sequencing centers, a Model Organisms Screening Center, a Metabolomics Core, a central … diseases at the NIH Clinical Center. Model Organisms Screening Center At the Model Organisms Screening Center, …
Educational Resources
Fact sheets explaining complex concepts in genomics research to a non-scientific audience.
… DNA Sequencing, Epigenomics, Knockout Mice, Newborn Screening, Cost Of Sequencing A Human Genome, X Chromosome, Y …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) aims to identify all functional elements in the human and mouse genomes.
… Institute of Technology University of California, Irvine High Precision Human and Mouse Transcriptomes UM1 HG009443 … William Greenleaf Michael Bassik Stanford University High-throughput systematic characterization of regulatory … components: Functional Element Mapping Centers Conduct high-throughput experiments that map biochemical activities …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… identify new genetic targets against the disease. Current screening of possible anti-metastasis compounds is based on … against cancer cell lines in laboratory dishes. Such high-throughput screening has identified thousands of drug …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… on an organism lacking it. Such larger scale - termed high-throughput - gene targeting in an animal model could be … lab.) This produced mutations in 82 of the 83 genes. In screening embryos by fluorescent polymerase chain reaction (a …
Staff
Dr. Shawn Burgess is the co-deputy director of NHGRI's Intramural Research Program.
… genes. The Burgess group developed new techniques for high-throughput identification of retroviral integration sites, … over which genes are inactivated. As a result, targeted screening in a vertebrate is now possible for the first time, … Chen, Raman Sood, Johan Ledin and Shawn M. Burgess. High-throughput gene targeting and phenotyping in zebrafish …
Intramural Training Office
Three-minute talk (TmT) presentation videos from previous years dating back to 2015.
… Fellow, Medical Genetics Branch  Development of a high-throughput framework to improve the replicability of … for Advancing Translational Sciences  Novel Label-free High Throughput Drug Repurposing Screen Jaqueline Picache … tissue model of the lower respiratory tract for high-throughput screening of anti-viral agents Esther Sim …
Event
The Advances in Genomic Technology Development (AGTD) 2022 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) from July 12-14, 2022 at The Jackson Laboratory (Farmington, CT).
… in Human Cells: Systematic Development and Testing with High-Throughput Methods Lacramioara Bintu, Ph.D. Stanford University 10:10 a.m. High Throughput, Multiplexed Epigenomic Profiling of Primary …
Staff
Stacie Anderson is an associate director in the Office of Scientific Core Facilities and is also the director of the Flow Cytometry Core. ​
… goal of providing all NHGRI investigators with access to high quality flow cytometry services to enhance the scope and … transcription profiles including scRNAseq, as well as high throughput screening of enhancer regions. …
News Release
A team from the NIH has surmounted a major obstacle to testing potential drug therapies for a rare, genetic condition called Gaucher disease.
… They identified the small molecule compound through high-throughput screening, which tests hundreds of thousands of small …