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Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
15 Ways Genomics Influences Our World
Genomics is advancing the study of individual and communities of microbes.
… can make a big difference in the severity of someone's infection. Beyond influenza, the most advanced genomics … in our world, since in the most extreme cases of infection with antibiotic-resistant bacteria can lead to … can also go wrong with your gut microbiome, such as when infection with the bacterium H. pylori  leads to ulcers - …
Staff
Dr. Jennifer Troyer is the director of NHGRI's Division of Extramural Operations.
… virus induced CD4+ T-cell depletion by prior infection with a non-pathogenic virus. Virology, … SJ. Patterns of feline immunodeficiency virus multiple infection and genome divergence in a free-ranging population …
Genetic Disorders
Velocardiofacial syndrome is the most common syndrome associated with a cleft palate.
… in the palate; heart defects; problems fighting infection; low calcium levels; differences in the way the … percent), heart defects (75 percent), problems fighting infection (77 percent), low calcium levels (50 percent), …
News Release
A new study highlights how genomic mutations that cause mitochondrial disease may also compromise affected people's immune response.
… response. The mutations resulted in an increased risk of infection and reduced protective immunity after vaccination, … to be researchers, too... The NIH MINI Study: Metabolism, Infection and Immunity in Inborn Errors of Metabolism …
For Patients and Families
​Pharmacogenomics combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.​
… problem can cause severe side effects and increase risk of infection, unless the standard dose is adjusted according to … as others, resulting in severe diarrhea and increased infection risk. Such patients may need to receive lower doses …
Research at NHGRI
An international investigation into the genetics of severe acute malnutrition in children.
… no consistently reproducible differences in environment, infection status, or diet. KwashNet is undertaking the first …
News Release
A new study offers insights into why some people's hair goes gray in response to a serious illness or chronic stress.
… When a body is under attack from a viral or bacterial infection, the body's innate immune system kicks into gear. … both mouse models to a substance that mimicked a viral infection. The melanocytes with less MITF had a stronger …
Genetic Disorders
Turner syndrome is a chromosomal condition that alters development in females.
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… The Metabolism, Infection and Immunity Section (MINIS) studies the interplay … metabolism is based on the clinical observation that infection is a major cause of metabolic decompensation and … Clinical Center, called the NIH MINI Study: Metabolism Infection and Immunity in IEM (NIH Clinical Trial …