Search Results
FAQ
On September 6, 2023, the National Human Genome Research Institute hosted a pre-application webinar for the genomics-enabled learning health systems (gLHS) NOFOs: RFA-HG-23-041 and RFA-HG-23-042. Questions were answered during the webinar.
Profile
An interview with Meru Sadhu, an Earl Stadtman Investigator and head of the systems biology and genome engineering section within the NHGRI Intramural Research Program, where he talks about his research and why yeast have a special place in his heart.
AnVIL
The Data Use Oversight System (DUOS) is a semi-automated study registration and DAR management service informed by the GA4GH DUO standard, which enables the secondary use of human genomics and other controlled-access data in compliance with the informed consent of a study’s participants.
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
Staff
Dr. Lanata is a staff clinician in NHGRI's Genomics of Autoimmune Rheumatic Disease Section.
… she worked as a Senior Research Assistant at the Hopkins Lupus Center. Dr. Lanata completed her residency in Internal … genomics in the field of autoimmunity with expertise in Systemic Lupus Erythematosus (SLE), with national and international … genomics, and environmental influences in the context of Systemic Lupus Erythematosus (SLE) outcomes, with a …
Genetic Disorders
Antiphospholipid Syndrome is a disorder characterized by elevated levels of antibodies that are associated with clots in the arteries and veins.
… APS. These are called anticardiolipin antibodies and the lupus anticoagulant, and are directed against specific … have false-positive tests for syphilis went on to develop systemic lupus erythematosus (SLE) and other similar conditions. Later … with APS as well. Conditions associated with APS include: Systemic Vascular Thrombosis While the deep veins of the legs …
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
Staff
Dr. Dan Kastner is an NIH Distinguished Investigator in Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch.
… established a research group in the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) that … mutated in the dominantly-inherited syndrome of pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) encodes a … form of STAT4  increases genetic susceptibility to rheumatoid arthritis and systemic lupus erythematosus. N …
Clinical Research
A Longitudinal Natural History Study of Children with Mitochondrial Disease (at the NIH Clinical Center).
The Genomics Landscape
In the October 2018 edition of The Genomics Landscape, NHGRI Director Dr. Eric Green highlights Dr. Dan Kastner as the Federal Employee of the Year.
… to common disorders such as Behçet's disease, rheumatoid arthritis, and systemic lupus erythematosus. Since the beginning of his …