Search Results
News Release
NIH researchers and collaborators have found that that sickle cell trait is prevalent among diverse human populations.
… Study finds that sickle cell trait is prevalent among diverse human populations. … collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait , increases … also known as venous thromboembolism. Through statistical analyses, participants were grouped based on their genetic …
Educational Resources
Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded.
… (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded. … Cell, Genetic Code, Deoxyribonucleic Acid (DNA), Protein, … to DNA. Unlike DNA, however, RNA is most often single-stranded. An RNA molecule has a backbone made of … (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded. …
Fact Sheet
Learn about the different types of hemoglobin.
… To understand sickle cell disease and gene therapy , you should first know about … Hemoglobin types and sickle cell disease  Your red blood cells contain hemoglobin , a … oxygen to your body’s organs and tissues. Every red blood cell contains thousands of hemoglobin molecules.   The …
Educational Resources
Apoptosis is the process of programmed cell death.
… Apoptosis is the process of programmed cell death. … Programmed Cell Death, Development, DNA Repair, Cancer, Tumor, Cell Division … Apoptosis is the process of programmed cell death. It is used during early development to eliminate … is for some reason prevented, it can lead to uncontrolled cell division and the subsequent development of a tumor. …
Research Funding
Funded in 2016 to harmonize, access, and analyze the data produced by the sequencing centers.
… undertake novel, investigator-initiated computational analyses on GSP data and develop methods to discover variants … Medicine Program  to harmonize joint variant calls and analyses, functional annotations, and phenotypic information. …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… is a collection of all the gene readouts present in a cell. … is a collection of all the gene readouts present in a cell. There are various kinds of RNA. The major type, called … to ribosomes , the molecular machines located in the cell's cytoplasm; then the ribosomes read, or "translate," …
Educational Resources
A point mutation is when a single base pair is altered.
… A point mutation is when a single base pair is altered. … A point mutation occurs in a genome when a single base pair is added, deleted or changed. While most … A point mutation is when a single base pair is altered. …
News Release
Genomic analyses turned up genes that belong to inflammatory pathways.
… translated). In this case, the effect leads to a form of cell death that causes inflammation. Dr. Kastner had a hunch … Center staff. "The genes that turned up in the genomic analyses of the disease we focus on belong to inflammatory … Genomic analyses turned up genes that belong to inflammatory pathways. …
Educational Resources
The nucleolus is a region found within the cell nucleus that is concerned with producing and assembling the cell's ribosomes.
… The nucleolus is a region found within the cell nucleus that is concerned with producing and assembling the cell's ribosomes. … Messenger RNA (mRNA), Ribonucleic Acid (RNA), Translation, Cell, Cytoplasm, Protein, Nucleus, Ribosome … The nucleolus is a spherical structure found in the cell’s nucleus whose primary function is to produce and …
News Release
In a study published in the journal Science, collaborators at NHGRI, the National University of Ireland, Galway, and the Whitney Laboratory for Marine Bioscience at the University of Florida, Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ cells in a cycle that can repeat endlessly.
… genes. Piwi1-positive spermatogonia are shown in yellow; cell nuclei are in turquoise. Germ cell induction and all stages of gametogenesis can be … Hydractinia . Piwi1-positive oocytes are shown in yellow; cell nuclei are in turquoise. Germ cell induction and all …