Search Results
Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.
… population descriptors — race, ethnicity and genetic ancestry — which are often used to distinguish groups of … on the distinctions between race, ethnicity and genetic ancestry, and to advance the use of population descriptors in … Latino or Spanish for ethnicity, and White, Black or African American, American Indian or Alaskan Native and Asian …
Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… in children, and is found more often among populations of African- or Hispanic ancestries. Children with COEH are … our risk locus. We are also applying trans- and local-ancestry admixture mapping models to other cohorts of … project funded by the NIH, Wellcome Trust, and African Academy of Sciences (AAS) known as the Human Health …
Event
On November 5-9, 2024, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition. The annual meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics.
… Genome Sequencing YieldsNovel Insights into SARS-CoV-2 in African Americans 5097F Jiayu Fu Phasing Accuracy of … reveals islet cell depletion exacerbated in individuals of African ancestry with Type 2 diabetes 5169F Tam Tran Efficient large … Talk: Genetic Determinants of Liver Function Markers in African Ancestry Populations Speaker, Reagan Mogire 1:15 – …
Research at NHGRI
CRGGH facilitates understanding of the relationship between genetic variation and population differences in disease distribution to inform health disparities.
… different human populations with particular attention to African Americans and Africans. … of Africa is highlighted to depict the emphasis of our ancestry and to remind us that the human race has a common … to reinforce that studying the genetic makeup of the African population will lend tremendous insight into the …
News Release
In an article published in the American Journal of Human Genetics, researchers have found that words scientists use to describe populations have changed from 1949 to 2018.
… reveals that use of the term “race” has declined, while “ancestry” and “ethnicity” have increased. … use to describe human populations — such as race, ancestry, and ethnicity — significantly changed from 1949 to … has increased over time. Geographic-based terms like “African,” “Asian” and “European” are also on the rise. …
About Genomics
Appropriate use of population descriptors in scientific research is critical for the advancement of genomic science and human health for all.
… benefits, and challenges in using race, ethnicity, ancestry, and other population descriptors in genomics … Read the Report: Use of Race, Ethnicity, and Ancestry as Population Descriptors in Genomics Research … of population descriptors, their relation to genetic ancestry, their use in society throughout the last few …
Fact Sheet
Participation in genomics research is essential for improving the health of everyone.
… for their DNA to be used for research are from European ancestry, making many populations from across the globe … for genomics research have been overwhelmingly of European ancestry, which creates gaps in knowledge about the genomes … to lowest): 78% European; 10% Asian; 8.5% Unreported; 2% African; 1% Hispanic; and 0.5% Other Countries The …
News Release
NHGRI researchers have successfully used facial recognition software to diagnose a rare, genetic disease in known as DiGeorge syndrome.
… atlas featured photos of patients with northern European ancestry, which often does not represent the characteristics …
News Release
NHGRI researchers collaborated with physicians and medical geneticists worldwide to create the Atlas of Human Malformation Syndromes in Diverse Populations.
… and descriptions of people with the same condition and ancestry. … atlas featured photos of patients with northern European ancestry, which often does not represent the characteristics … in Africa. "We found ourselves struggling to diagnose the African children," Dr. Kruszka said. "We were doing our best …
News
To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.
… more accurately assess disease risk regardless of genetic ancestry. … the scores often heavily overrepresent people of European ancestry. “Recently, more and more studies incorporate multi-ancestry genomic data into the development of polygenic risk …