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Educational Resources
Genetic drift is a mechanism of evolution. It refers to random fluctuations in the frequencies of alleles from generation to generation due to chance events.
… Genetic Drift, Evolution, Population Genetics, Genes …
Educational Resources
The Human Genome Project was an international project that mapped and sequenced the entire human genome.
… Human Genome Project … The Human Genome Project was an international project that mapped and sequenced the entire human genome. … Human Genome Project, Francis Collins, DNA, Genomics, Base … effort that mapped and sequenced the human genome for the first time. Conducted from 1990 to 2003, the project …
15 Ways Genomics Influences Our World
Genomics is illuminating human and family origins at a level not previously possible.
… Genomics is illuminating human and family origins at a level not previously possible. … your ancestors, both near and distant? Advances since the Human Genome Project allow us to compare genome sequences … among the most common questions that humans ponder. The Human Genome Project produced a reference human genome …
News Release
In a new large-scale genetic analysis, National Institutes of Health (NIH) scientists have found set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type 2 diabetes.
… found a set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type … the basic biology of pancreatic islets is important for human health. The study, led in part by scientists at the … Collins, M.D., Ph.D., senior investigator in the Center for Precision Health Research in NHGRI’s Intramural Research …
Policy Issues
Payers such as insurance companies and Medicare need systematic ways of evaluating genetic tests for reimbursement.
… For patients to have full access to the benefits of genetic … Medicare need systematic ways of evaluating genetic tests for reimbursement. … Procedural Terminology (CPT) codes developed by the American Medical Association, and fewer than 200 CPT codes … Secretary's Advisory Committee on Genetics, Health, and Society) An Evidence Framework for Genetic Testing  (National …
Research at NHGRI
The Genetics and Molecular Biology Branch uses genomic technologies to study the human genome and other organisms and disease mechanisms.
… The Genetics and Molecular Biology Branch uses state-of-the-art … into improved diagnosis, treatments and prevention of human diseases. Using the excellent resources of NHGRI … have allowed our investigators to develop clinical trials for gene therapy of immune deficiency and preclinical …
For Patients and Families
​Genetic tests may be used to identify increased risks of health problems, to choose treatments, or to assess responses to treatments.
… disease Identify gene changes that are responsible for an already diagnosed disease Determine the severity of a … in deciding on the best medicine or treatment to use for certain individuals Identify gene changes that may … that could be passed on to children Screen newborn babies for certain treatable conditions Genetic test results can be …
Educational Resources
The Genetic Information Nondiscrimination Act (GINA) is federal legislation that makes it unlawful to discriminate against individuals on the basis of their genetic profiles in regard to health insurance and employment.
Educational Resources
A genetic map is a type of chromosome map that shows the relative locations of genes and other important features.
Policy Issues
Most genetic tests today are not regulated, meaning that they go to market without any independent analysis to verify the claims of the seller.
… tests: the Food and Drug Administration (FDA), the Centers for Medicare and Medicaid Services (CMS), and the Federal … criteria, adapted from the National Library of Medicine's Genetics Home Reference . Analytical Validity: Refers to how … the tests. It also comprises proficiency testing for some tests. More information about CLIA is available in …