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News Release
NHGRI researchers have produced the first end-to-end DNA sequence of a human chromosome. The results show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers to produce a complete sequence of the human genome.
… This accomplishment opens a new era in genomics research. … Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes … incredibly long, consisting of about 6 billion bases, DNA sequencing machines cannot read all the bases at once. …
Clinical Research
The Institutional Review Board (IRB)Â is responsible for protecting the rights and welfare of the human subjects of research protocols that are conducted by intramural investigators in NHGRI and a number of other institutes.
… protecting the rights and welfare of the human subjects of research protocols that are conducted by intramural … Oversight for human subjects research happening in the National Human Genome Research Institute (NHGRI) is provided by a centralized NIH … An Introduction to Radiation for NIH Research Subjects NIH Clinical Research Studies Active Consent / Assent Documents …
The Genomics Landscape
In the February 2019 edition of The Genomics Landscape, NHGRI Director Eric Green recognizes Dr. Bill Gahl's achievements as Clinical Director.
… from being a Center (the National Center for Human Genome Research). That means NHGRI just turned 22 years old as an … strategic planning process, a workshop focusing on the research opportunities for connecting genomic variation to … After ~16 years as Clinical Director within NHGRI's Intramural Research Program, …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… The Social and Behavioral Research Branch (SBRB) aims to develop optimal approaches for the integration of genomic discoveries into clinical and community contexts. … through using animal models to explore these connections. Clinical translation of genomic discovery We approach …
News Release
A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional practices for validating DNA sequencing results.
… A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional practices for validating DNA sequencing results. The research suggests that newer, faster, … may have important implications for the DNA sequencing of clinical samples, and perhaps affect the diagnostic pipeline …
Clinical Research
FAQs for Autoinflammatory Diseases Study providers and researchers.
… on new genetic discoveries. We can search our database of clinical and genetic data to see if we have a match. We may … Ivona Aksentijevich if you would like to further discuss research opportunities. … Clinical Research …
News Release
NHGRI has appointed Neil Hanchard, M.D., Ph.D., as a clinical investigator within the Medical Genomics and Metabolic Genetics Branch (MGMGB) in the Division of Intramural Research. Dr. Hanchard will head the Childhood Complex Disease Genomics Section within the MGMGB.
… The National Human Genome Research Institute (NHGRI) has appointed Neil Hanchard, M.D., Ph.D., as a clinical investigator within the Medical Genomics and … His efforts will integrate laboratory-based and clinical methods to study several pediatric diseases, … Dr. Neil Hanchard joins NHGRI as a clinical investigator …
Fact Sheets
Estimated cost of sequencing the human genome over time since the Human Genome Project.
… have led to substantial reductions in the cost of genome sequencing. The underlying costs associated with different methods and strategies for sequencing genomes are of great interest because they influence the scope and scale of almost all genomics research projects. …
Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… The NIH Intramural Sequencing Center (NISC) , established in 1997, is a … procedures. NISC's role within the National Human Genome Research Institute (NHGRI), and more broadly across NIH, aims … methods to analyze genomics data with applicability to clinical and basic science questions that were thought to be …
News Release
A new genome-based technology for demystifying undiagnosed illnesses - even rare childhood diseases - is moving into general medical practice.
… - particularly rare childhood diseases - is moving from research laboratories into general medical practice. Now, two … "This primer illustrates how rapidly the use of genome sequencing has moved into clinical practice," said NHGRI Director Eric D. Green, M.D., …