Search Results
15 Ways Genomics Influences Our World
Genomics is illuminating human and family origins at a level not previously possible.
… Genomics is illuminating human and family origins at a level not previously possible. … Did you know that your genome helps uncover the history of your ancestors, both near and distant? Advances since the Human Genome Project allow us to compare genome sequences …
News Release
Researchers and clinicians are sequencing human genomes faster than ever, so considering the societal implications of genomic data is even crucial.
… Implications (ELSI) Research Program at the National Human Genome Research Institute, launched in 1990 with the … cure auto-immune diseases or permanently change your DNA sequence. From NIH-NHGRI Thanks for the question! This is … Researchers and clinicians are sequencing human genomes faster than ever, so considering the societal …
News Release
A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional practices for validating DNA sequencing results.
… A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional … to supplant Sanger sequencing because of its ability to sequence millions of pieces of DNA at the same time - … The current standard "best practice" in some clinical genome sequencing laboratories requires positive NGS findings …
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule. … the general laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule. The … understanding the function of genes and other parts of the genome. There are now several different methods available for …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… researchers use a variety of tools to compare the complete genome sequences of different species. By carefully comparing … of years - is an important step toward understanding the genome itself. It pinpoints genes that are essential to life … turn may translate into innovative approaches for treating human disease and improving human health. Comparative …
Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… - called "bases" - that make up the DNA molecule. The sequence tells scientists the kind of genetic information … by which most DNA sequencing experiments are done. The human genome contains about 3 billion base pairs that spell out the … Since the completion of the Human Genome Project, technological improvements and …
Research Funding
GS-IT provides sequence analysis tools and software to scientists who rely on genomics in their research.
… researchers. This includes software dedicated to sequence quality, alignment, assembly, variant calling, … Genome Sequencing Informatics Tools (GS-IT) provides "researcher friendly" sequence analysis tools and software to a broad community of … Genome Sequencing Informatics Tools …
Talking Glossary
Next-generation DNA sequencing (abbreviated NGS) refers to the use of technologies for sequencing DNA that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method of Sanger sequencing).
… that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method … that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method … that became available shortly after the completion of the Human Genome Project (which relied on the first-generation …
News Release
A team of NIH-funded researchers have generated the first complete chromosome sequences from non-human primates.
… generated the first complete chromosome sequences from non-human primates. Published in Nature , these sequences uncover … Ph.D., a postdoctoral fellow at the National Human Genome Research Institute (NHGRI), part of NIH, and an author of the study. “Only the chimpanzee genome sequence was fairly complete before this, but even that still …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… essentially unchanged in >20 years: provide contemporary genome-sequencing capabilities for intramural researchers at … that mission, regularly generating large amounts of genome-sequence data and analyses for numerous NHGRI and NIH … . Later, NISC became involved in NIH Common Fund's Human Microbiome Project , in which genome sequencing was …