Search Results
The Genomics Landscape
In the January 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly developed polygenic risk scores webpage, which provides graphical and textual information about polygenic risk scores, describes polygenic traits, introduces how polygenic risk scores can be calculated, and explains how such scores can be interpreted.
… – Tracy Swan Exploring the role of ribosome biogenesis in regeneration – Sofia Barreira Funding Opportunities NIH seeks …
The Genomics Landscape
In the February 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the December 2021 NHGRI symposium's success in confronting the difficult pasts of eugenics and scientific racism.
… The Genotype-Tissue Expression (GTEx) project generated NHGRI’s most …
FAQ
Questions and answers from the September 26, 2022, Multi-Omics for Health and Disease Consortium Pre-Application Webinar.
… allowed to collect multiple types of biospecimens, such as tissue, blood or urine? More than one sample type (as many as … in RFA-HG-22-009.  Is there a requirement for different tissue types? Collecting both blood and tissue, for example, may double the samples required. There …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… - also called gene expression - in a certain cell or tissue type. In humans and other organisms, nearly every cell … in cell growth. Or if an unknown gene is expressed in fat tissue but not in bone or muscle tissue, the unknown gene may be involved in fat storage or …
Fact Sheets
Un transcriptoma es una colección de todas las lecturas de genes presentes en una célula​​. ​
… Proyecto de expresión del genotipo en tejidos ( Genotype-Tissue Expression Project , GTEx) y la Enciclopedia de los …
File
… Concept Clearance for FOAs: Developmental Genotype-Tissue Expression (dGTEx) …
Staff
William J. Pavan, Ph.D. is the chief of NHGRI's Genetic Disease Research Branch.
… impact towards understanding adult stem cells, regeneration medicine and melanoma research. To identify … also evaluate the effects these gene mutants have on other tissue types. Together, these studies will increase …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… out in an ES cell, the effects can be observed in any tissue in an adult mouse. In addition, ES cells grown in the …
The Genomics Landscape
In the November 2023 edition of The Genomics Landscape, NHGRI Director Eric Green, celebrates the 30th anniversary of the NHGRI Intramural Research Program as well as announces the launch of a new digital history archive.
… researchers at the University of Chicago highlight tissue-specific regulation of genes that lead to differences …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… large-scale analysis of all the proteins in an organism, tissue type, or cell (called the proteome). Proteomics can be … blastocyst have the ability to develop into every type of tissue (skin, liver, kidney, blood, etc.) found in an adult … patient's immune system may react and reject the donated tissue as "foreign." However, by using stem cells, there may …