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News Release
Researchers have discovered that FGF21 is elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia.
… activated and can impair their ability to respond to acute stress," said Irini Manoli, M.D., Ph.D., lead author …
Staff
Dr. Manfred Boehm is a an adjunct investigator for the Office of the Clinical Director at NHGRI.
… LE, San H, Chen G, St Hilaire C, Boehm M. Stat3-dependent acute Rantes production in vascular smooth muscle cells …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Layla received a gene editing treatment to help her fight leukemia, a type of cancer. These scientists did not use …
News Release
Celebrating 30 years of genomics that has transformed our understanding of life and improved health.
… to make quick diagnoses of rare genetic disorders in acute settings. Another notable achievement since the end of …
News Release
A new phase of the IGNITE Network will conduct clinical trials of genomic medicine interventions.
… issues, the study seeks to test whether patients with acute post-surgical pain, chronic pain and depression have …
Research Funding
A list of members who contribute to the goals of the IGVF Consortium by generating data and/or analyses, sharing data and/or analyses freely through the IGVF Data and Administrative Coordinating Center (DACC), and/or by contributing to cross- consortium integrative analyses.
… non-coding sequence variation associated with pediatric leukemia. We plan to dissect non-coding regulatory elements … genes and describe their function in hematopoiesis and leukemia.  Tychele Turner, Washington University in St. …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… to serious problems. For example, in humans, one type of leukemia and some other cancers are caused by defective …
Research Funding
The IGNITE PTN supports a network of multi-site clinical groups involving diverse settings and populations to conduct two pragmatic clinical trials of genomic medicine interventions.
… approaches to drug therapy selection ("usual care") for acute post-surgical pain, chronic pain, and depression via …
File
… RUNX1 Familial Platelet Disorder with Associated Myeloid Malignancies …
News Release
Researchers from NHGRI, Oxford University and other National Institutes of Health centers have developed and tested a new method to predict hospital-acquired infections involving five other important pathogens.