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Educational Resources
Fluorescence in situ hybridization (FISH) is a laboratory technique for detecting and locating a specific DNA sequence on a chromosome.
… for detecting and locating a specific DNA sequence on a chromosome. … Laboratory Experiment, DNA Sequence, Chromosome, Microscopy … used to detect and locate a specific DNA sequence on a chromosome. In this technique, the full set of chromosomes … of chromosomes. With the use of a special microscope, the chromosome and sub-chromosomal location where the fluorescent …
Educational Resources
Mitosis is a cellular process that replicates chromosomes and produces two identical nuclei in preparation for cell division.
… Mitosis, Meiosis, Cell Biology, DNA, Chromosome …
Educational Resources
A candidate gene is a gene whose chromosomal location is associated with a particular disease or other phenotype.
… Genes, Chromosome, Phenotype, Traits, Disease, Linkage Analysis …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… discovered that a CBFB-MYH11 fusion gene is the product of chromosome 16 inversion, a common chromosome abnormality in human acute myeloid leukemia. Using … each year, leukemias are frequently associated with chromosome abnormalities such as translocations, inversions …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… A physical map of a chromosome or a genome that shows the physical locations of … Chromosome, Gene, Deoxyribonucleic Acid (DNA), Positional … variants and other DNA sequences of interest) within a chromosome or genome. A complete genome sequence is one type … A physical map of a chromosome or a genome that shows the physical locations of …
Educational Resources
Mapping is the process of making a representative diagram cataloging the genes and other features of a chromosome and showing their relative locations.
… diagram cataloging the genes and other features of a chromosome and showing their relative locations. … Genetic Mapping, Recombinant DNA, Genes, Chromosome … variants and other DNA sequences of interest) within a chromosome or genome. Historically, there have been two …
Genetic Disorders
Klinefelter syndrome is a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility.
… a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility. … a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility. Humans … (This is written as XX.) Males have an X and a Y chromosome (written as XY). The two sex chromosomes help a …
Educational Resources
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
… physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. … Locus, Allele, DNA Polymorphism, Gene, Chromosome … physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. …
Educational Resources
A genetic map is a type of chromosome map that shows the relative locations of genes and other important features.
… A genetic map is a type of chromosome map that shows the relative locations of genes and … Genetic Map, Chromosome, Genes, Linkage Analysis, Family Health History … markers (reflecting sites of genomic variants) on a chromosome. A genetic map is based on the concept of genetic …
Educational Resources
Positional cloning is a laboratory technique used to locate the position of a disease-associated gene along the chromosome.
… locate the position of a disease-associated gene along the chromosome. … Candidate, Gene, Chromosome, Contig, Deoxyribonucleic Acid (DNA), Gene, Linkage … to locate the position of a disease-associated gene on a chromosome. Such a strategy can succeed even when nothing is …