Search Results
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… a variety of conditions, including heart disease, breast cancer, and hearing loss. … volunteers for the study. Each member of the study has a clinical visit and tests to look at heart health. Study … CLINSEQ®? Possible benefits to you may include: Free clinical testing, such as testing for cholesterol and …
Graduate Medical Education
An opportunity for a 4-to-8-week elective in the National Human Genome Research Institute (NHGRI) at the NIH Clinical Center in Bethesda, MD.
… Alcohol Use Disorders Biomedical Informatics Cardiology Clinical Pharmacology and Therapeutics for Senior Medical Students Critical Care Medicine Endocrinology and Metabolism Health Services … Medical Genetics Medical Oncology Neuro-Oncology Neurology/Clinical Neuroscience …
Talking Glossary
Un gen de susceptibilidad al cáncer es un gen que, cuando cambia (o muta) confiere a la persona un mayor riesgo de desarrollar cáncer.
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… as the PanCancer Atlas, on a data set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer. … Francis S. Collins, M.D., Ph.D. "This analysis provides cancer researchers with unprecedented understanding of how, … and why tumors arise in humans, enabling better informed clinical trials and future treatments." The Pan-Cancer Atlas, …
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
… Prostate Cancer … Prostate cancer is a disease characterized by uncontrolled cell growth … Cancer, Cell, Mitosis, Mutation … Prostate cancer is a disease characterized by uncontrolled cell growth … which is part of the male reproductive system. Prostate cancer generally affects men over the age of 50. It is …
Secondary Genomics Finding Service
Clinical Research Staff and Protocol Coordinators
… that variants in 59 genes be returned to people undergoing clinical sequencing - this is frequently referred to as the … annotation and return of actionable secondary findings in clinical sequencing; contains the "ACMG 59 gene list"  … Clinical Research Staff and Protocol Coordinators …
Profile
NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
…  We know from previous research that primary care providers generally don’t have a lot of experience with … risk information as less healthy and in need of more care. We’ve seen that in the past, in which genomic risk … almost as a pre-diagnosis.  Lastly, we saw differences in clinical recommendations based on patient race. For example, …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
…  After more than a decade, The Cancer Genome Atlas (TCGA) program is drawing to an end. A … initiated and supported by NHGRI and the National Cancer Institute (NCI), with over $300 million in total … and why tumors arise in humans, enabling better informed clinical trials and future treatments. As the program draws …
FAQ
On October 10, 2024, NHGRI hosted a pre-application webinar for the Population Genomic Screening in Primary Care NOFOs: RFA-HG-24-021, RFA-HG-24-022, and RFA-HG-24-023. These FAQs contain questions answered during that webinar.
… award. CGs should not budget for DNA extraction.  What clinical variant types will be screened? Specifically, will … CNVs and structural variants be returned?  The type of clinical variants to be screened and returned will be decided … current Tier 1 conditions (hereditary breast and ovarian cancer or HBOC, Lynch syndrome or LS, and familial …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research … More information on TCGA can be found on NCI’s The Cancer Genome Atlas Program website . The Cancer Genome Atlas … NIH completes in-depth genomic analysis of 33 cancer types  (2018)  The Cancer Genome Atlas publishes …