Search Results
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… Sally Adebamowo*, Michele Ramsay, Bamidele Tayo Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study … Cohorts and Novel Methods to Improve Polygenic Risk Scores Massachusetts General Hospital Amit Khera … Members of the Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will …
Profile
NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
… Study shows genomic information can unknowingly influence medical … study? Susan Persky: Researchers are increasingly using genomic data in the clinic for diagnosing rare health … common health conditions, information such as polygenic risk scores are not currently as accurate at predicting risk. …
Leadership Initiatives
The Genomics and Health Disparities Interest Group provides a forum to connect individuals from different scientific disciplines across the National Institutes of Health (NIH) and researchers in the Washington D.C. metropolitan area engaged in genomics and health disparities research, as well as provide opportunities for professional development, networking and community engagement.
… The Genomics and Health Disparities Interest Group provides a forum to … disciplines across the National Institutes of Health (NIH) and researchers in the Washington D.C. metropolitan area engaged in genomics and health disparities research, as well as provide …
News Release
In honor of Rare Disease Day, experts from the UDN turned to Reddit to answer questions during an "Ask me Anything."
… from the UDN turned to Reddit - a social news website and discussion forum - to answer questions from the Reddit … Clinical and research experts from the Undiagnosed Diseases Network … missed days of work, hospital stays, lab tests, and the risk of injury from hunting for a disease. Also, what are …
News Release
Genomic variants that increase risk of kidney disease are found in nearly one-third of West Africans
A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people of West African ancestry.
… from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people from Ghana and … Research Network. Previous research established that genomic variants in APOL1 increase the risk of developing …
News
To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.
… Improved genetic tests more accurately assess disease risk regardless of genetic ancestry. … To prevent an emerging genomic technology from contributing to health disparities, a … NIH’s Electronic Medical Health Records and Genomics (eMERGE) Network will continue this research by enrolling a …
News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
… have a gene variant associated sickle cell trait (SCT) and most never have related health complications. Researchers … conditions for which people with SCT are at increased risk. … genes with environmental exposures that may increase risk for some individuals." Hematologists and sickle cell …
The Genomics Landscape
In the January 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly developed polygenic risk scores webpage, which provides graphical and textual information about polygenic risk scores, describes polygenic traits, introduces how polygenic risk scores can be calculated, and explains how such scores can be interpreted.
… addition to meeting with numerous researchers, students, and government leaders, I gave four talks – specifically, at … research collaborations to tackle major challenges in genomic and precision medicine. It will be important to have India’s genomic researchers involved in those international efforts. …
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.
… To productively use a long, blank (and boring) hallway near my office in Building 31 on the NIH … sequence – specifically, about 3 million G’s, A’s, T’s, and C’s stretching nearly 100 linear feet. As mentioned in a … Oct. 15-19, 2019; a workshop on “Integrating the Past and Future of ELSI Research” at the American Society of …
News Release
NIH awarded grants to six medical centers to select from the most difficult-to-solve medical cases and develop effective approaches to diagnose them.
… to select from the most difficult-to-solve medical cases and together develop effective approaches to diagnose them. The clinical sites will conduct clinical evaluation and scientific investigation in cases that involve patients … of patients and provided many diagnoses, often using genomic approaches, for rare conditions. "Newly developed …