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Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… Genetic Disease, Genetic Disorder, Gene Mutation, Cancer Treatment, Healthcare … Gene therapy is a technique that uses a gene(s) to treat, prevent or cure a disease or medical disorder. …
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
… Prostate Cancer … Prostate cancer is a disease characterized by uncontrolled cell growth … Cancer, Cell, Mitosis, Mutation … Prostate cancer is a disease characterized by uncontrolled cell growth … which is part of the male reproductive system. Prostate cancer generally affects men over the age of 50. It is …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… from over 10,000 tumors representing 33 types of cancer. … cells (in pink), illustrating a primary tumor spreading to other parts of the body through the circulatory system. … clustering, which groups tumors by parameters such as genes being expressed, abnormality of chromosome numbers in …
Educational Resources
Gene mapping is the process of establishing the locations of genes on the chromosomes.
… mapping is the process of establishing the locations of genes on the chromosomes. … Gene mapping refers to the process of determining the location of genes on chromosomes. Today, the most efficient approach for … mapping is the process of establishing the locations of genes on the chromosomes. …
NACHGR
Links to past NHGRI Director's Report-Related Documents.
… 2024 September 2024 Director's Report-Related Documents May 2024 Director's Report-Related Documents February 2024 Director's Report-Related Documents 2023 September 2023 Director's Report … Past Director's Report-Related Documents …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
… Last month, I was deeply flattered to receive an honorary Doctor of Science degree from … 2018 Commencement. This honor was particularly meaningful to me as a St. Louis native and a former medical student, … University, and I am grateful for my extensive ties to this outstanding institution. As the summer begins, NHGRI …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… process by which the information encoded in a gene is used to direct the assembly of a protein molecule. … Gene expression be thought of as an “on/off switch” to control when and where RNA molecules and proteins are made … and cell types. The RNA and protein products of many genes serve to regulate the expression of other genes. Where, …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number of new … about the biology and development of a rare form of kidney cancer. … cell carcinoma (ChRCC) - stems in part from alterations in genes in the mitochondria, the cell's energy supplier. They …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… of gene function and the identification of disease genes in humans, according to scientists at the National Human Genome Research Institute … In a study posted online on June 5, 2015, and to be published in the July 2015 issue of Genome Research , … effective than other techniques at homing in on target genes and inserting or deleting specific sequences. The study …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National … website . The Cancer Genome Atlas began with a pilot to assessed the feasibility of a full-scale effort to systematically explore the entire spectrum of genomic … of cervical cancer (2017) TCGA study reveals new clues to the genomic diversity of prostate cancers (2015) …