Search Results
News Release
NHGRI-funded CSER investigators and colleagues point to need for greater evidence that DNA sequencing helps patients.
… In the nearly four years since its launch, the Clinical Sequencing Exploratory Research (CSER) program has made … disease; improved the analysis and interpretation of DNA sequencing results; and provided new insights into the … Maryland, for a one-day conference, Integrating Genomic Sequencing into Clinical Care: CSER and Beyond . The meeting …
News Release
NHGRI convened geneticists, biologists, clinicians, bioinformatics specialists and more to provide expert advice on the future of its Genome Sequencing Program.
… provide expert advice on the future of its flagship Genome Sequencing Program (GSP). … two-day meeting, titled, Future Opportunities for Genome Sequencing and Beyond: A Planning workshop for the National … clinic. In addition to the long-established Large-Scale Sequencing and Analysis Center (LSAC) program, the GSP now …
Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… The NIH Intramural Sequencing Center (NISC) , established in 1997, is a … Institutes of Health (NIH) access to well established, high-throughput DNA sequencing, NISC works closely with NIH … NIH Intramural Sequencing Center … The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility …
Talking Glossary
Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule.
… Nanopore DNA Sequencing … Nanopore DNA sequencing is a laboratory technique for determining the … Nanopore DNA sequencing is a laboratory technique for determining the … that cells use to develop and operate. Nanopore DNA sequencing involves reading the code of single DNA strands as …
News Release
A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional practices for validating DNA sequencing results.
… is challenging traditional practices for validating DNA sequencing results. The research suggests that newer, faster, "next-generation" DNA sequencing (NGS) methods are as accurate - and perhaps more accurate - than Sanger sequencing, a time-tested technique that is typically used to …
Talking Glossary
The genome reference sequence provides a general framework and is not the DNA sequence of a single person.
Talking Glossary
RNA-seq, short for RNA sequencing, is a method for sequencing an entire set of RNA molecules.
… RNA-seq (RNA Sequencing) … RNA-seq, short for RNA sequencing, is a method for sequencing an entire set of RNA molecules. … RNA-seq, short for RNA sequencing, is a method for sequencing an entire set of RNA molecules. This method … RNA-seq, short for RNA sequencing, is a method for sequencing an entire set of RNA …
Research Funding
A collaborative large-scale genome sequencing effort to identify rare risk and protective variants contributing to multiple common disease phenotypes.
… Genomics (CCDG) are a collaborative large-scale genome sequencing effort to comprehensively identify rare risk and … informatics tools, and innovative approaches and technologies for multiple disease research communities and … Collaborative large-scale genome sequencing effort to identify rare risk and protective …
News Release
Ten investigators will receive exome sequencing data as part of their clinical research projects at the NIH Clinical Center.
… Ten intramural investigators will receive exome sequencing data as part of their clinical research projects … NIH Clinical Center. Using CCGO funds, the NIH Intramural Sequencing Center will sequence the exomes of 1,000 NIH Clinical Center patients. Exome sequencing explores the 1-2 percent of the genome that codes …
News Release
Researchers developed a technique that will aid in a more accurate reconstruction of human genomes.
… a genome from the much smaller pieces of DNA that sequencing machines are able to read, much like putting … For example, the Angus breed evolved to produce a very high-quality beef product, while the Brahman breed, emerging … technology. The parents' genomes are first sequenced using high-accuracy short reads to determine which parts of their …