Search Results
News Release
Scientists studying the genomes of nearly 5,000 people have pinpointed a genetic variant tied to an increased risk for stroke and cardiovascular disease.
… details about an important metabolic pathway that plays a major role in several common diseases. Together, their … ). Stroke is the fourth leading cause of death and a major cause of adult disability in this country, yet its … participants in the FHS, a remarkable result given the complex nature of methionine metabolism and its impact on …
Research at NHGRI
CRGGH uses genomic tools to understand the pathobiology of metabolic disorders, including obesity, hypertension, diabetes, dyslipidemia, and kidney disease.
… with "new" environments in the evolution of common complex traits. … allow novel inquiries into the evolutionary context of complex human diseases. For example, CRGGH investigators … predispose individuals and populations to chronic complex diseases such diabetes and cardiovascular disorders. …
Virtual Exhibit
The Human Genome Project changed traditional understandings of how and why scientific research is conducted. It was, however, not without its detractors. Early in 1990, there was an effort to stop funding for the nascent Human Genome Project, in the form of a letter writing campaign.
The Genomics Landscape
In April 6, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how NHGRI will hold a symposium on National DNA Day, April 25, highlighting relevant and interesting topics in genomics and concluding with the annual Louise M. Slaughter National DNA Day Lecture.
… questions about our evolutionary history, health, and complex issues surrounding individual and group identity … to characterize their genetic ancestry and found large, complex families of dogs living in both locations. This study … Director Eric Green, M.D., Ph.D. , that will include other major NIH leaders: Diana Bianchi, M.D. , Eunice Kennedy …
News Release
NIH leaders are calling for the scientific community to develop a consensus on the appropriate use of race and ethnicity in biomedical research.
… and ethnic categories in biomedical research is part of a complex and sometimes contentious conversation about how … data and its appropriate use in biomedical research. Major NIH efforts are also underway to enhance representation …
National Advisory Council for Human Genome Research
The Director's Report-Related Documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in February 2023.
… Resolved Epigenomic Profiling of Single Cells in Complex Tissues" Jones et al. – "High-Throughput CRISPRi and … Genetics to Cancers, Joan Bailey-Wilson Retires After Major Advances in Hematology, David Bodine Retires with an … Family of Unusual Immunoglobulin Genes in an Invertebrate Histocompatibility Complex" 60 ‘One-Stop-Shop’ to Stay …
About Genomics
The History of Genomics Program collects and organizes historic materials related to the field of genomics and NHGRI as an organization.
… artifacts from the Human Genome Project and other major genomics efforts. To receive more information about … Scholarly descriptions and analyses of the major genomics programs and other NHGRI endeavors strive to …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… Media Availability Complex traits such as height and susceptibility to common … gene activity in mice and humans, as well as the cause of complex traits and disease in both species. The research was …
Event
On October 25-29, 2022, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.
… Location Wednesday, October 26, 2022 3:00 p.m. — 4:45 p.m. Complex Traits Classical HLA Alleles are Associated with … Exhibit Hall 3:00 p.m. — 4:45 p.m. Reviewer's Choice/ Complex Traits Quantification of race, ethnicity, and genetic … Genetics and Genetic Epidemiology Local Ancestry at the MHC region id asscociated with disease heterogeneity in …
News Release
Celebrating 30 years of genomics that has transformed our understanding of life and improved health.
… to zoom. The Human Genome Project (HGP) Timeline contains major milestones in genomics from 1865 to 2003. Credit: … a catalog of human genes and beginning to understand the complex choreography involved in gene expression. The growing …