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Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data.
… data on gene expression, as well as surrogate markers of regulatory elements, in different cell fates or cell states. … expression and functional element data to construct gene regulatory network models, taking advantage of the dynamics … this area, which is to be able to predict, just by reading DNA sequence, when and at what level a gene is expressed, in …
15 Ways Genomics Influences Our World
Advances in genomics are reducing the cost of genome sequencing by a million-fold.
… our understanding of evolution. Our genome (that is, our DNA "blueprint") - and in fact the genomes of all life forms … To study the exact order (or sequence ) of someone's DNA, researchers follow three major steps: (1) purify and copy the DNA; (2) read the sequence; and (3) compare to other …
Talking Glossary
While some sequencing technologies produce reads that are only a few hundred nucleotides long, some methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.”
… Long-Read DNA Sequencing … of thousands of nucleotides long, known as “long-read DNA sequencing.” … DNA sequencing technologies determine the order of the base pairs in fragments of DNA known as “reads”. Scientists must then piece these reads … of thousands of nucleotides long, known as “long-read DNA sequencing.” …
The Genomics Landscape
In the April 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 15th anniversary of National DNA Day and the '15 for 15' Celebration.
… community will celebrate a yearly highlight - National DNA Day. On this day, students, teachers, and the public are … lives and what the future holds. This year's National DNA Day features an exciting assortment of online and … Time); a Facebook Live broadcast of NHGRI's National DNA Day speaker, Dr. Olivier Noel (CEO of DNA Simple) on …
Event
The Excellence in Clinical Research Seminar Series is designed to facilitate clinical research in the rare disease space with a focus on aspects of regulatory medicine and clinical trials in Mendelian disorders.
… research in the rare disease space with a focus on regulatory medicine and clinical trials in Mendelian … publication or (2) an interview with a leader in regulatory medicine and clinical trials. The seminars aim to … are not limited to): study design, preclinical research, regulatory affairs, data management, funding/budgets, working …
Event
NHGRI commemorates the life and legacy of genomics champion Representative Louise M. Slaughter (D-N.Y.), who passed away in March 2018, by naming an annual National DNA Day lecture at the National Institutes of Health (NIH) in her honor.
… in the House of Representatives that created National DNA Day, which celebrates the completion of the Human Genome Project and the anniversary of the discovery of DNA's iconic structure, the double helix. As one of the … passed away in March 2018 - by naming an annual National DNA Day lecture at the National Institutes of Health (NIH) in …
News Release
Researchers funded by NIH have completed a detailed atlas documenting stretches of human DNA that influence gene expression.
… a detailed atlas documenting the stretches of human DNA that influence gene expression - a key way in which a … biobank of collected tissue samples, as well as extracted DNA and RNA for future studies by independent researchers. … NIH completes atlas of human DNA differences that influence gene expression …
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… but most of the alterations are found in regions of the DNA that do not carry genes. Scientists have suspected that the variants are in DNA elements called enhancers, which act like switches to … V, O'Shea JJ. Super-enhancers delineate disease-associated regulatory nodes in T cells . Nature . Online February 16, …
The Genomics Landscape
In the May 2019 edition of The Genomics Landscape, NHGRI Director Eric Green recaps activities from National DNA Day 2019.
… joins the rest of the country in celebrating National DNA Day, which commemorates two historical milestones: the … of the Human Genome Project in 2003 and the discovery of DNA’s iconic double-helical structure in 1953. This year, … and how those advances relate to people’s lives. National DNA Day activities were certainly present on the NIH Campus …
Event
On April 25, 2023, NHGRI hosted a symposium to commemorate two special milestones: the 20th anniversary of the Human Genome Project’s completion and the 70th anniversary of the discovery of the DNA double helix.
… About DNA Day DNA Day Activity Ideas Find a DNA Day event near you Plan your own DNA Day event … and the 70th anniversary of the discovery of the DNA double helix. The symposium explored the evolution and … concluded with the annual Louise M. Slaughter National DNA Day Lecture. Follow #NHGRIevents and #DNADay23 on social …