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Jim Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics.
… Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics. … are you most proud of? Jim Mullikin: Of course, the Human Genome Project is one of the top ones. I started working on … finished just before I moved to NHGRI in 2003. Seeing the whole progress, from the very early days of Sanger sequencing …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… Researchers with the National Human Genome Research Institute (NHGRI) and their collaborators … proteins that fix damage to DNA. The research team used whole genome sequencing, a process that reveals the complete DNA make-up … cancer, genomic signatures, Elaine Ostrander Ph.D., whole genome sequencing, BRCA2 gene, PARP inhibitors …
News Release
NIH is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care for all individuals.
… towards research that aims to accelerate the use of genome sequencing in clinical care. The new awards will generate … The research is being funded as part of the Clinical Sequencing Evidence-Generating Research (CSER2) Consortium. … , initiated in 2010 and funded by the National Human Genome Research Institute (NHGRI) and the National Cancer …
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… Genome-wide detection of somatic mosaicism at short tandem … While the cells in our bodies largely share the same genome, some cells can have genomic differences. This … repeats. The researchers applied the tool to study 460 whole-genome sequences, revealing hundreds of mosaic short …
Talking Glossary
Next-generation DNA sequencing (abbreviated NGS) refers to the use of technologies for sequencing DNA that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method of Sanger sequencing).
… Next-Generation DNA Sequencing … Next-generation DNA sequencing (abbreviated NGS) refers to the use of technologies for sequencing DNA that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method … became available shortly after the completion of the Human Genome Project (which relied on the first-generation method …
News Release
Jeffery Schloss, Ph.D., founding director of the Division of Genome Sciences, is embarking on a new journey: retirement.
… After an extraordinary career at the National Human Genome Research Institute (NHGRI), Jeffery Schloss, Ph.D., founding director of the Division of Genome Sciences, is embarking on a new journey: retirement. … for a program director at the National Center for Human Genome Research (NCHGR), what is now known as NHGRI. He …
News Release
NHGRI researchers have produced the first end-to-end DNA sequence of a human chromosome. The results show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers to produce a complete sequence of the human genome.
… Researchers at the National Human Genome Research Institute (NHGRI), part of the National … researchers to produce a complete sequence of the human genome.   “This accomplishment begins a new era in genomics … incredibly long, consisting of about 6 billion bases, DNA sequencing machines cannot read all the bases at once. …
News Release
NIH lost a key member of its broader genomics team when Robert Blakesley, Ph.D., director of the NISC sequencing group at NIH, retired on Dec. 31, 2015.
… 31 retirement of Robert Blakesley, Ph.D., director of the sequencing group at the NIH Intramural Sequencing Center (NISC) in Rockville, Maryland. … Eric Green, M.D., Ph.D., director of the National Human Genome Research Institute (NHGRI), part of NIH. "When I …
Talking Glossary
Nanopore DNA sequencing is a laboratory technique for determining the exact sequence of nucleotides, or bases, in a DNA molecule.
… Nanopore DNA Sequencing … Nanopore DNA sequencing is a laboratory technique for determining the … Nanopore DNA sequencing is a laboratory technique for determining the … that cells use to develop and operate. Nanopore DNA sequencing involves reading the code of single DNA strands as …
News Release
New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome.
… the most comprehensive reference sequence of the human genome. The awards, made over five years pending the … availability of funds, are managed by the National Human Genome Research Institute (NHGRI), part of the National … The currently available reference sequence of the human genome is becoming obsolete. The funds are necessary for …