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Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… have created a promising new method to accurately and, in some cases, more comprehensively analyze and interpret DNA sequence information from cancer patients. They have developed an algorithm that sorts … to their clinical and biological relevance to a patient's cancer. …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… of Health researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted … research on mice with a rare disease similar to one in humans, hoping their findings may eventually help improve … an association between AAV and the occurrence of liver cancer. The present research addresses this problem in gene …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number … about the biology and development of a rare form of kidney cancer. … of the 66 ChRCC tumors studied, a high number for a rare cancer. The study revealed increased numbers of mitochondria …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… and Ph.D. from The Indian Institute of Science, India in 1983. He completed his postdoctoral training at the University of Illinois at Chicago in molecular virology, and at the University of Chicago in … genomic research for NHGRI investigators. As head of the Cancer Genomics Unit, his research efforts led to the …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… Dr. Meltzer is a leader in the application of genome science to cancer research. His recent studies investigate the genetic and epigenetic basis of cancers in adult and pediatric patients, particularly those with bone … Asian Hepatocellular Carcinoma and Cholangiocarcinoma . Cancer Cell , 32(1):57-70.e3. 2017. Killian JK, Dorssers LC, …
Talking Glossary
Un carcinógeno es una sustancia, organismo o agente capaz de causar cáncer.
Talking Glossary
BRCA1 y BRCA2 son los dos primeros genes que se identificaron como asociados a tipos hereditarios del cáncer de mama y de ovario. Las personas con mutaciones en BRCA1 o BRCA2 tienen un riesgo mucho más alto de desarrollar cáncer de mama, de ovario u otros tipos de cáncer en comparación con las personas que no tienen mutaciones en estos genes.
Talking Glossary
Un oncogén es un gen que sufrió una mutación y que tiene el potencial de causar cáncer.
Event
Annual scientific lecture honoring NHGRI's founding scientific director, Jeffrey M. Trent, Ph.D.
… MIT and Harvard, will present the lecture, Perspectives on Cancer Precision Medicine . Dr. Golub is a world leader in using genomics tools to understand the basis of cancer. He also pioneered the development of new cell-based … of Medicine, delivered the lecture  Evolution of Germline Cancer Genomics from Rare Disorders to Precision Oncology …