Search Results
Fact Sheet
Learn about the different types of hemoglobin.
… bone marrow . White blood cells are part of the body's immune system; they help the body fight infection and other …
Research at NHGRI
The Genetic Disease Research Branch studies how genetic changes affect the structure and function of gene products leading to human disease.
… human diseases, particularly those affecting the nervous, immune and musculoskeletal systems. As a major emphasis of …
Clinical Research
NHGRI researchers work with patients and families to explore how genes cause or influence diseases, and develop more effective diagnostics and treatments.
News Release
Daniel Kastner, M.D., Ph.D., Scientific Director for the Intramural Research Program at the National Human Genome Research Institute (NHGRI) recognized for his pioneering work on the genomics of autoinflammatory diseases.
… inflammation and tissue damage, affecting the nervous system, skin and joints. Affected individuals can eventually … a separate branch of immunity called the innate immune system. Therefore, it became clear that autoinflammatory …
Fact Sheet
Viruses are bundles of genetic material wrapped in a protein coat that can infect living things.
… the probability and pace by which they evade the human immune system. In other cases, two different viruses interested in … proteins, the active component of the vaccine to which the immune system responds. When injected, these DNA or RNA molecules …
FAQ
Addressing the COVID-19 pandemic and what it means to the pediatric mitochondrial disease community.
… disease. We evaluate their infection risk and immune function, and we document any complications that …
News Release
NHGRI researchers have discovered clues to the possible cause of recurring, non-contagious fevers and sores that affect only children. Several genes have been implicated with the syndrome, known as PFAPA syndrome (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis), which could lead to new treatments.
… an inflammation-related protein that is used by the immune system. The IL12A protein acts as an alarm for the immune system and prompts an inflammatory response by …
The Genomics Landscape
In the October 2018 edition of The Genomics Landscape, NHGRI Director Dr. Eric Green highlights Dr. Dan Kastner as the Federal Employee of the Year.
… illnesses, proposed a now widely-accepted explanation for immune disorders, identified critical insights into innate … include discovering new molecules in the human innate immune system and providing important insights into their function; …
News Release
NHGRI researchers and colleagues are calling for health disparities research that focuses on the microbiome.
… habits and sleep patterns. Stress, its impact on the immune system and its role on disease risk is another important area … that the microbiome may change in response to the immune system and vice versa. In response, they propose a …
Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.
… used to inappropriately group people into a hierarchical system to "establish and justify systems of power, privilege, … . Race has been used to group people into a hierarchical system that identifies, distinguishes and marginalizes some …