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Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project developed patient-focused educational materials for the sickle cell community.
… Education for Sickle Cell Disease Gene Therapy Project, which is led by NHGRI in partnership with other … This project created patient-focused education materials for the … Education for Sickle Cell Disease Gene Therapy Project, which is led by NHGRI in partnership with other …
News Release
NHGRI researchers have produced the first end-to-end DNA sequence of a human chromosome. The results show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers to produce a complete sequence of the human genome.
… Researchers at the National Human Genome Research Institute (NHGRI), part of the National … have produced the first end-to-end DNA sequence of a human chromosome. The results, published today in the journal … show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers …
News Release
ENCODE program directors in the Division of Genome Sciences turned to Reddit to answer questions from the Reddit community.
… The National Human Genome Research Institute's ENCyclopedia Of DNA Elements (ENCODE) Project has spent 13 years building a catalog of all the functional elements in the human genome sequence , and making it available to scientists … Reddit AMA: The ENCODE Project …
Research Funding
The Knockout Mouse Phenotyping Project (KOMP2) collaborates with the International Mouse Phenotyping Consortium (IMPC) to knockout and characterize all protein-coding genes in the mouse genome.
… Laboratory Knockout Mouse Production and Phenotyping Project (JAX KOMP2) OD023222 Dickinson, Mary E Heaney, Jason … Medicine The BCM Knockout Mouse Production and Phenotyping Project (BCM KOMP2) HG006348 Lloyd, KC Kent University of … The Knockout Mouse Phenotyping Project (KOMP2) is a trans-NIH initiative that aims to …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… Databases such as the 1000 Genomes Project and the Exome Aggregation Consortium (ExAC) harbor … The Genomic Ascertainment Cohort (TGAC), a two-year pilot project that will allow them to recall genotyped people and … to them. NIH will establish a new database of 10,000 human genomes and exomes, the 1-2 percent of the genome that …
News Release
In August 2022, NHGRI History of Genomics Program celebrates 10 years of chronicling how the field of genomics began and evolved, with a particular emphasis on the role of NHGRI.
… In September 2008, the National Human Genome Research Institute (NHGRI) was experiencing a … one of the most important undertakings in science, the Human Genome Project, as well as a series of major genomics initiatives … Capturing the history of the Human Genome Project and beyond …
MINC
The MINC Toolkit assists those interested in integrating genomics into practice.
The Genomics Landscape
In the July 2020 edition of The Genomics Landscape, NHGRI Director Eric Green recalls the White House event announcing the draft human genome sequence.
… to announce the completion of a draft sequence of the human genome. The ceremony took place in the East Room of the … gathered to celebrate a major milestone for the Human Genome Project. This historic landmark for biomedical research was … reports directly into the U.S. Department of Health and Human Services.  …
Staff
Dr. Colin Fletcher is the program director in the Knockout Mouse Project (KOMP) in NHGRI's Extramural Research Program.
… principally responsible for supervising The Knockout Mouse Project (KOMP). The goal of the KOMP program, expected to be … is now working to implement The Knockout Mouse Phenotyping Project (KOMP2). The goal of this program is to covert the … by multiple Institutes. Prior to joining the National Human Genome Research Institute (NHGRI), Dr. Fletcher was a …
Event
NHGRI, NICHD, NIMH, and ORIP program staff held a pre-application webinar with an interactive Q&A session for the Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project.
… RFH-HG-21-026 - Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project (U24 Clinical Trials Not Allowed) … heterogeneity as possible. How will we coordinate with human dGtex? Indicate in your proposal what is needed to coordinate effectively with the Human dGTEx project . Since this is a transcriptome resource, what is the …