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… nucleic acid sequencing technologies for DNA and direct RNA sequencing. Advances in genomics and more broadly in … Exhaustive and quantitative sequencing of every DNA and/or RNA molecule in a sampl e. • Very long reads (e.g., ≥150 Kb) … -01 R43 DAPPRICH, JOHANNES Amplification -Free Target Enrichment and Direct Sequencing of Large Chromosomal …
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… technologies that allowed for the creation of synthetic RNA and DNA. With the viral sequence in hand, these … Messenger RNA (mRNA) is a molecule that encodes a sequence that can be …
News Release
Researchers funded by NHGRI’s Genome Technology Program include a wide range of investigators with a variety of scientific expertise.
… With a renewed interest in understanding RNA and delving deeper into its biology, including a focus on RNA sequence and modifications, here are snippets of some exciting RNA-focused projects that are supported by NHGRI’s Genome … nanopore sequencing , involves threading strands of DNA or RNA nucleotides through small pores within a membrane, …
News Release
NIH is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care for all individuals.
Event
The Advances in Genomic Technology Development (AGTD) 2022 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) from July 12-14, 2022 at The Jackson Laboratory (Farmington, CT).
… Update: Programmable Eukaryotic Protein Expression with RNA Sensors Omar Abudayyeh, Ph.D. Massachusetts Institute of … of Washington 1:30 p.m. A Novel Approach for Studying RBP-RNA and RBP-RBP Interactions at Isoform and Single-Molecule … Dinner  Wednesday, July 13, 2022  Time Topic Speaker RNA Sequencing: Part I Session Moderators: Xiaoxu Li, Ph.D., …
Event
The Advances in Genomic Technology Development (AGTD) 2023 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) in-person and virtually from Tuesday, June 6, until Thursday, June 8, at The Sanford Consortium for Regenerative Medicine, La Jolla, CA.
… Salk Institute for Biological Studies 8:45 a.m. STAMPing RNA binding protein-RNA networks Gene Yeo, Ph.D., MBA University of California, … Update: Programmable Eukaryotic Protein Expression with RNA Sensors Omar Abudayyeh, Ph.D. Massachusetts Institute of … Time Topic Speaker 8:30 a.m. Keynote: Global insights into RNA nucleotide variants, isoforms and stability Xinshu …
Fact Sheet
Early in the COVID-19 pandemic, researchers used state-of-the-art genomic sequencers to quickly sequence the SARS-CoV-2 virus.
… First, they separate the two strands of plasmid DNA. Then, RNA polymerase, the molecule that transcribes RNA from DNA, uses the spike protein gene to create a single …
Fact Sheet
Genomic research has been central to understanding and combating the SARS-CoV-2 (COVID-19) pandemic.
… virus, which is the pathogen that causes COVID-19, uses RNA as its genetic material. First, the PCR is converted from single-stranded RNA to double-stranded DNA in a process called reverse … of DNA copies corresponding to the SARS-CoV-2 viral RNA. … so it is unlikely a sample will be positive if viral RNA is not present. If it does, it is called a false positive …
Staff
Jennifer Strasburger was the lead Genomic Program Administrator (GPA) for NHGRI as well as the co-chair for the NHGRI Data Access Committee (DAC).
… in 2020. She managed a portfolio of grants focused upon RNA epitranscriptomic modifications and technology … development proposals to accelerate understanding of RNA function in complex biological systems and to harness RNA research to advance biotechnology. Prior to joining …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… Transcription is the process of making an RNA copy of a gene sequence. This copy, called a messenger RNA (mRNA) molecule, leaves the cell nucleus and enters the … is the process of translating the sequence of a messenger RNA (mRNA) molecule to a sequence of amino acids during …