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News Release
Scientists studying the genomes of nearly 5,000 people have pinpointed a genetic variant tied to an increased risk for stroke and cardiovascular disease.
… fellow at the University of Virginia Cardiovascular Research Center and the University of Virginia Center for … investigators were supported by the National Human Genome Research Institute (NHGRI) Genomics and Randomized Trials … prevent a second ischemic stroke, and the Framingham Heart Study (FHS), which has followed the cardiovascular health and …
Research at NHGRI
NHGRI's research focuses on the understanding of human biology and developing new methods for treating disease.
… The National Human Genome Research Institute (NHGRI) conducts a broad program of laboratory and clinical research to translate genomics into a greater understanding … Research Areas … The National Human Genome Research Institute's research focuses on the understanding of …
Clinical Research
In the late 90’s and early 2000’s, scientists at the NIH highlighted an increased incidence of Parkinson disease among patients with GD and their families.
… Mutations in Parkinson’s Disease ”, where the study demonstrated that mutations in the GBA1 gene give … Further understanding of this risk is a main focus of research of our team. … Compensation: There is no compensation provided for this study. Travel: Cost of hotel and associated travel to and …
Clinical Research
FAQs for participants in the Autoinflammatory Diseases Study.
… What does study participation look like? We tailor study activities to … for parents of affected children Leukapheresis (rare) Research bone marrow aspiration and biopsy (rare; age 12 or … genetic cause for a patient’s disease, we will continue to research their data in the lab and compare it to that of …
News Release
The largest genomic study on type 2 diabetes in Africans to date has recently been published in Nature Communications and reports the most recent findings of the ongoing Africa America Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades.
… The largest genomic study on type 2 diabetes in Africans to date has recently … of the ongoing Africa America Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two … The present study, co-first-authored by Dr. Adebowale Adeyemo of … stewardship of the multi-country, multi-institutional AADM study has included Dr. Ayo Doumatey, Dr. Guanjie Chen, Jie …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
… Study of millions of people from diverse ancestral groups … In a large-scale study of people from diverse ancestries, researchers narrowed … authors include researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes … on the paper and NHGRI staff scientist at the Center for Research on Genomics and Global Health. “In addition to …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… values. In 2008, Dr. Shriner joined the Center for Research on Genomics and Global Health within the National Human Genome Research Institute, National Institutes of Health. Methodological research includes the development of methods for … A., and Rotimi, C. N. 2011. A genome-wide association study of serum uric acid in African Americans. BMC Med. …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… The Social and Behavioral Research Branch (SBRB) aims to develop optimal approaches for … Our research focuses on a spectrum of disorders from those that … We approach research with a social genomics lens. We study a diverse group of disorders and seek to find how …
Policy Issues
Participating in genomics research is an opportunity to support exploration of the genome and help scientists understand, prevent, detect and treat disease.
… Participating in genomics research is an opportunity to support scientific exploration … prevent, detect and better treat disease. In some cases, research participants may also gain some individual benefit, … A wide range of genomic research studies need participants, each with different …
Policy Issues
Federally-funded research with human participants must comply with regulations that protect the rights and welfare of the participants.
… participants in biomedical, clinical and social-behavioral research can provide insights and discoveries that could not … model organisms or other methods. All federally-funded research with human participants such as that supported by … clarify the benefits and risks of participating in the research. …