Search Results
News Release
More research must be done to understand the interactions of ancient genes with modern environments.
… sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of … groups of people. The average percentage of African ancestry in the Americas varies widely: 87 percent in African … percent in Puerto Ricans, 7 percent in people with Mexican ancestry in Los Angeles and 4 percent in both Peruvians in …
Event
Several NIH Institutes, Offices and Centers partnered to host a two-day virtual workshop on May 28-29, 2024, to further explore the recommendations from the National Academies of Sciences, Engineering and Medicine (NASEM) 2023 report, Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field, with regards to legacy genomic data. 
Staff
Dr. Charles Rotimi is the scientific director of and NIH Distinguished Investigator in the Division of Intramural Research. He also serves as the director of the Center for Research on Genomics and Global Health (CRGGH).
… with particular emphasis on populations of African ancestry. The Africa America Diabetes Mellitus (AADM) study, … the association signals found in European and Asian ancestry populations; it has provided some of the earliest … the etiology of diabetes and related traits in African ancestry populations. CRGGH published the first GWAS for …
File
… Ancestry and Disease in the Age of Genomic Medicine (October …
News Release
The TCGA network describes uterine and bile duct cancer.
… characteristics of breast cancer by African and European Ancestry. This paper identifies molecular differences by genetic ancestry, most of which can be captured by known breast … Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas Large data set brings …
Staff
Dr. Meeks is a Special Volunteer at the Center for Research on Genomics and Global Health.
… in underrepresented populations, in particular African-ancestry populations. These innovative designs include … and epigenetic biomarkers in type 2 diabetes among African-ancestry populations. …
News Release
eMERGE Network will support multiple clinical sites and a coordinating center with $75 million over five years.
… that almost exclusively involved people of European ancestry. It is not clear how well the findings from these … studies can be used for risk assessment in non-European ancestry populations.  In addition, calculating polygenic …
Staff
Dr. Gouveia is a research fellow in the Center for Research on Genomics and Global Health.
… to account for subcontinental admixture in European-ancestry populations can lead to spurious associations in …
Fact Sheet
A fact sheet detailing how the project began and how it shaped the future of research and technology.
… majority of the sequence came from one person of blended ancestry. Specifically, 70 percent of the original reference … a combination of 19 other individuals of mostly European ancestry. …
News Release
An international team of researchers including NIH has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa.
… to medical conditions in people of sub-Saharan African ancestry, and indicates that the migration from Africa in the … conducted that include populations with mainly European ancestry." The GWAS approach involves rapidly scanning … the few studies that have been conducted among African-ancestry populations have used less efficient genotyping …