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Staff
Dr. Merideth is a staff clinician in the Office of the Clinical Director and program director for both the NHGRI Medical Biochemical Genetics Fellowship and
NHGRI Clinical Biochemical Genetics Fellowship.
News Release
NIH researchers identified a novel role for a gene known as heat shock protein 60, finding it is critical in tissue regeneration and wound healing.
… molecule that induces an inflammatory response to bacterial infection from a cut. "A major problem is that …
Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
… - especially young children - easily overwhelmed by bacterial infections. A baby born with sickle cell disease …
Virtual Exhibit
The Gene Sweepstakes — or GeneSweep as it became popularly known — was a three-year-long, sweepstakes-style contest organized by British bioinformatician Ewan Birney, Ph.D., of the European Bioinformatics Institute. Scientists participated in the contest by betting on the total number of protein-coding genes that would be identified in the human genome sequence generated by the Human Genome Project.
… we had to iteratively keep searching for and mapping BACs [Bacterial Artificial Chromosomes] that overlapped the two … to be all about acid and stuff like that. Actually, it's a bacterial infection. So, there's lots of these things. …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… scientists and clinicians sort out the mystery  of a bacterial outbreak in the NIH Clinical Center. In 2013, NISC …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… typically involves propagating the recombinant DNA in a bacterial or yeast cell, whose cellular machinery copies the …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… to a pattern of DNA sequences that appears frequently in bacterial DNA. Scientists believe the CRISPR sequences …
Staff
Dr. Sergey Koren is an associate Investigator in the Genome Informatics Section of the Center for Genomics and Data Science Research.
… for high-quality assembly. This work has revolutionized bacterial genome assembly, giving complete and accurate …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… of a modified viral vector or a linear fragment of bacterial DNA. After the artificial DNA is inserted, the …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.