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… IBS, ulcerative colitis, Crohn’s DiseaseUrogenital:bacterial vaginosis, circumcision, sexual histories Microbial … Alzheimer’s, autism, psychiatric disordersVa g i n a : bacterial vaginosis, preterm birthMicrobiome(s) and … Recent advances in microbiome research*üGut bacteria/bacterial metabolism and obesityüBacterial metabolism and …
Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
… - especially young children - easily overwhelmed by bacterial infections. A baby born with sickle cell disease …
News Release
NIH researchers identified a novel role for a gene known as heat shock protein 60, finding it is critical in tissue regeneration and wound healing.
… molecule that induces an inflammatory response to bacterial infection from a cut. "A major problem is that …
Virtual Exhibit
The Gene Sweepstakes — or GeneSweep as it became popularly known — was a three-year-long, sweepstakes-style contest organized by British bioinformatician Ewan Birney, Ph.D., of the European Bioinformatics Institute. Scientists participated in the contest by betting on the total number of protein-coding genes that would be identified in the human genome sequence generated by the Human Genome Project.
… we had to iteratively keep searching for and mapping BACs [Bacterial Artificial Chromosomes] that overlapped the two … to be all about acid and stuff like that. Actually, it's a bacterial infection. So, there's lots of these things. …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… scientists and clinicians sort out the mystery  of a bacterial outbreak in the NIH Clinical Center. In 2013, NISC …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… typically involves propagating the recombinant DNA in a bacterial or yeast cell, whose cellular machinery copies the …
Staff
Dr. Sergey Koren is an associate Investigator in the Genome Informatics Section of the Center for Genomics and Data Science Research.
… for high-quality assembly. This work has revolutionized bacterial genome assembly, giving complete and accurate …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… of a modified viral vector or a linear fragment of bacterial DNA. After the artificial DNA is inserted, the …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… to a pattern of DNA sequences that appears frequently in bacterial DNA. Scientists believe the CRISPR sequences …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.